PubMed for id: 19219

Year	Number of Results
1973	1
1989	1
1993	1
1994	1
1995	1
1996	1
1997	5
1998	3
1999	3
2000	4
2001	5
2002	8
2003	8
2004	11
2005	15
2006	15
2007	8
2008	11
2009	13
2010	9
2011	14
2012	18
2013	13
2014	11
2015	16
2016	11
2017	10
2018	9
2019	8
2020	11
2021	3
2022	6
2023	3
2024	0

1

A novel role for PGE₂-EP₄ in the developmental programming of the mouse ductus arteriosus: consequences for vessel maturation and function.

Yarboro MT, Boatwright N, Sekulich DC, Hooper CW, Wong T, Poole SD, Berger CD, Brown AJ, Jetter CS, Sucre JMS, Shelton EL, Reese J. Yarboro MT, et al. Am J Physiol Heart Circ Physiol. 2023 Oct 1;325(4):H687-H701. doi: 10.1152/ajpheart.00294.2023. Epub 2023 Aug 11. Am J Physiol Heart Circ Physiol. 2023. PMID: 37566109 Free PMC article.

2

E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis.

Patankar JV, Müller TM, Kantham S, Acera MG, Mascia F, Scheibe K, Mahapatro M, Heichler C, Yu Y, Li W, Ruder B, Günther C, Leppkes M, Mathew MJ, Wirtz S, Neufert C, Kühl AA, Paquette J, Jacobson K, Atreya R, Zundler S, Neurath MF, Young RN, Becker C. Patankar JV, et al. Nat Cell Biol. 2021 Jul;23(7):796-807. doi: 10.1038/s41556-021-00708-8. Epub 2021 Jul 8. Nat Cell Biol. 2021. PMID: 34239062

3

Prostaglandin E receptor subtype 4 protects against diabetic cardiomyopathy by modulating cardiac fatty acid metabolism via FOXO1/CD36 signalling.

Ying F, Liu H, Ching Tang EH, Lakhani I, Liu N, Xia Z, Liu S. Ying F, et al. Biochem Biophys Res Commun. 2021 Apr 9;548:196-203. doi: 10.1016/j.bbrc.2021.01.038. Epub 2021 Feb 26. Biochem Biophys Res Commun. 2021. PMID: 33647796 Free article.

4

EP4 signalling is essential for controlling islet inflammation by causing a shift in macrophage polarization in obesity/type 2 diabetes.

Yasui-Kato M, Patlada S, Yokode M, Kamei K, Minami M. Yasui-Kato M, et al. Diab Vasc Dis Res. 2020 Jul-Aug;17(4):1479164120945675. doi: 10.1177/1479164120945675. Diab Vasc Dis Res. 2020. PMID: 32722929 Free PMC article.

5

Endothelial cell prostaglandin E2 receptor EP4 is essential for blood pressure homeostasis.

Xu H, Fang B, Du S, Wang S, Li Q, Jia X, Bao C, Ye L, Sui X, Qian L, Luan Z, Yang G, Zheng F, Wang N, Chen L, Zhang X, Guan Y. Xu H, et al. JCI Insight. 2020 Jul 9;5(13):e138505. doi: 10.1172/jci.insight.138505. JCI Insight. 2020. PMID: 32641583 Free PMC article.

6

Epithelial EP4 plays an essential role in maintaining homeostasis in colon.

Matsumoto Y, Nakanishi Y, Yoshioka T, Yamaga Y, Masuda T, Fukunaga Y, Sono M, Yoshikawa T, Nagao M, Araki O, Ogawa S, Goto N, Hiramatsu Y, Breyer RM, Fukuda A, Seno H. Matsumoto Y, et al. Sci Rep. 2019 Oct 23;9(1):15244. doi: 10.1038/s41598-019-51639-2. Sci Rep. 2019. PMID: 31645712 Free PMC article.

7

Role of prostaglandin E2 receptor 4 in the modulation of apoptosis and mitophagy during ischemia/reperfusion injury in the kidney.

Ding C, Han F, Xiang H, Wang Y, Dou M, Xia X, Li Y, Zheng J, Ding X, Xue W, Tian P. Ding C, et al. Mol Med Rep. 2019 Oct;20(4):3337-3346. doi: 10.3892/mmr.2019.10576. Epub 2019 Aug 8. Mol Med Rep. 2019. PMID: 31432142

8

VSMC-specific EP4 deletion exacerbates angiotensin II-induced aortic dissection by increasing vascular inflammation and blood pressure.

Xu H, Du S, Fang B, Li C, Jia X, Zheng S, Wang S, Li Q, Su W, Wang N, Zheng F, Chen L, Zhang X, Gustafsson JÅ, Guan Y. Xu H, et al. Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8457-8462. doi: 10.1073/pnas.1902119116. Epub 2019 Apr 4. Proc Natl Acad Sci U S A. 2019. PMID: 30948641 Free PMC article.

9

EP4 knockdown alleviates glomerulosclerosis through Smad and MAPK pathways in mesangial cells.

Cao Y, Pan T, Chen X, Wu J, Guo N, Wang B. Cao Y, et al. Mol Med Rep. 2018 Dec;18(6):5141-5150. doi: 10.3892/mmr.2018.9553. Epub 2018 Oct 12. Mol Med Rep. 2018. PMID: 30320390

10

Application of a dye-based mitochondrion-thermometry to determine the receptor downstream of prostaglandin E₂ involved in the regulation of hepatocyte metabolism.

Shen L, Xie TR, Yang RZ, Chen Y, Kang JS. Shen L, et al. Sci Rep. 2018 Aug 30;8(1):13065. doi: 10.1038/s41598-018-31356-y. Sci Rep. 2018. PMID: 30166566 Free PMC article.

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