PubMed for id: 108682

Year	Number of Results
1999	1
2000	4
2001	1
2002	2
2004	5
2005	2
2007	1
2008	1
2011	3
2015	1
2016	1
2018	1
2020	1
2022	4
2023	5
2024	0

1

Loss of mitochondrial enzyme GPT2 causes early neurodegeneration in locus coeruleus.

Baytas O, Kauer JA, Morrow EM. Baytas O, et al. Neurobiol Dis. 2022 Oct 15;173:105831. doi: 10.1016/j.nbd.2022.105831. Epub 2022 Jul 28. Neurobiol Dis. 2022. PMID: 35908744 Free PMC article.

2

Mitochondrial enzyme GPT2 regulates metabolic mechanisms required for neuron growth and motor function in vivo.

Baytas O, Davidson SM, DeBerardinis RJ, Morrow EM. Baytas O, et al. Hum Mol Genet. 2022 Feb 21;31(4):587-603. doi: 10.1093/hmg/ddab269. Hum Mol Genet. 2022. PMID: 34519342 Free PMC article.

3

Mutations in mitochondrial enzyme GPT2 cause metabolic dysfunction and neurological disease with developmental and progressive features.

Ouyang Q, Nakayama T, Baytas O, Davidson SM, Yang C, Schmidt M, Lizarraga SB, Mishra S, Ei-Quessny M, Niaz S, Gul Butt M, Imran Murtaza S, Javed A, Chaudhry HR, Vaughan DJ, Hill RS, Partlow JN, Yoo SY, Lam AT, Nasir R, Al-Saffar M, Barkovich AJ, Schwede M, Nagpal S, Rajab A, DeBerardinis RJ, Housman DE, Mochida GH, Morrow EM. Ouyang Q, et al. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5598-607. doi: 10.1073/pnas.1609221113. Epub 2016 Sep 6. Proc Natl Acad Sci U S A. 2016. PMID: 27601654 Free PMC article.

4

Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice.

Yiew NKH, Deja S, Ferguson D, Cho K, Jarasvaraparn C, Jacome-Sosa M, Lutkewitte AJ, Mukherjee S, Fu X, Singer JM, Patti GJ, Burgess SC, Finck BN. Yiew NKH, et al. iScience. 2023 Oct 12;26(11):108196. doi: 10.1016/j.isci.2023.108196. eCollection 2023 Nov 17. iScience. 2023. PMID: 37942005 Free PMC article.

5

Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult.

Yiew NKH, Vazquez JH, Martino MR, Kennon-McGill S, Price JR, Allard FD, Yee EU, Layman AJ, James LP, McCommis KS, Finck BN, McGill MR. Yiew NKH, et al. Mol Metab. 2023 Nov;77:101808. doi: 10.1016/j.molmet.2023.101808. Epub 2023 Sep 15. Mol Metab. 2023. PMID: 37716594 Free PMC article.

6

Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids.

Martino MR, Gutiérrez-Aguilar M, Yiew NKH, Lutkewitte AJ, Singer JM, McCommis KS, Ferguson D, Liss KHH, Yoshino J, Renkemeyer MK, Smith GI, Cho K, Fletcher JA, Klein S, Patti GJ, Burgess SC, Finck BN. Martino MR, et al. Cell Rep. 2022 Apr 26;39(4):110733. doi: 10.1016/j.celrep.2022.110733. Cell Rep. 2022. PMID: 35476997 Free PMC article.

7

Hepatic ALT isoenzymes are elevated in gluconeogenic conditions including diabetes and suppressed by insulin at the protein level.

Qian K, Zhong S, Xie K, Yu D, Yang R, Gong DW. Qian K, et al. Diabetes Metab Res Rev. 2015 Sep;31(6):562-71. doi: 10.1002/dmrr.2655. Epub 2015 Jun 17. Diabetes Metab Res Rev. 2015. PMID: 25865565 Free PMC article.

8

Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver.

Jadhao SB, Yang RZ, Lin Q, Hu H, Anania FA, Shuldiner AR, Gong DW. Jadhao SB, et al. Hepatology. 2004 May;39(5):1297-302. doi: 10.1002/hep.20182. Hepatology. 2004. PMID: 15122758

9

Exosomal GPT2 derived from triple-negative breast cancer cells promotes metastasis by activating BTRC.

Cui M, Peng J, Zhou Y, Wang X, Cui D. Cui M, et al. Thorac Cancer. 2023 Jul;14(21):2018-2025. doi: 10.1111/1759-7714.14984. Epub 2023 Jun 7. Thorac Cancer. 2023. PMID: 37287397 Free PMC article.

10

The delta subunit of the GABA_A receptor is necessary for the GPT2-promoted breast cancer metastasis.

Li N, Xu X, Liu D, Gao J, Gao Y, Wu X, Sheng H, Li Q, Mi J. Li N, et al. Theranostics. 2023 Feb 21;13(4):1355-1369. doi: 10.7150/thno.80544. eCollection 2023. Theranostics. 2023. PMID: 36923530 Free PMC article.

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