PubMed for id: 277264

Year	Number of Results
1995	1
1998	1
2001	1
2002	3
2005	1
2006	1
2007	1
2008	3
2009	4
2010	2
2011	1
2012	3
2013	5
2024	0

1

AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve.

Er EE, Mendoza MC, Mackey AM, Rameh LE, Blenis J. Er EE, et al. Sci Signal. 2013 Jun 11;6(279):ra45. doi: 10.1126/scisignal.2004015. Sci Signal. 2013. PMID: 23757022 Free PMC article.

2

PIKfyve sensitivity of hERG channels.

Pakladok T, Almilaji A, Munoz C, Alesutan I, Lang F. Pakladok T, et al. Cell Physiol Biochem. 2013;31(6):785-94. doi: 10.1159/000350096. Epub 2013 May 31. Cell Physiol Biochem. 2013. PMID: 23735862 Free article.

3

Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity, and hyperinsulinemia but not muscle fiber-type switching.

Ikonomov OC, Sbrissa D, Delvecchio K, Feng HZ, Cartee GD, Jin JP, Shisheva A. Ikonomov OC, et al. Am J Physiol Endocrinol Metab. 2013 Jul 1;305(1):E119-31. doi: 10.1152/ajpendo.00030.2013. Epub 2013 May 14. Am J Physiol Endocrinol Metab. 2013. PMID: 23673157 Free PMC article.

4

Critical roles of type III phosphatidylinositol phosphate kinase in murine embryonic visceral endoderm and adult intestine.

Takasuga S, Horie Y, Sasaki J, Sun-Wada GH, Kawamura N, Iizuka R, Mizuno K, Eguchi S, Kofuji S, Kimura H, Yamazaki M, Horie C, Odanaga E, Sato Y, Chida S, Kontani K, Harada A, Katada T, Suzuki A, Wada Y, Ohnishi H, Sasaki T. Takasuga S, et al. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1726-31. doi: 10.1073/pnas.1213212110. Epub 2013 Jan 15. Proc Natl Acad Sci U S A. 2013. PMID: 23322734 Free PMC article.

5

Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration.

Oppelt A, Lobert VH, Haglund K, Mackey AM, Rameh LE, Liestøl K, Schink KO, Pedersen NM, Wenzel EM, Haugsten EM, Brech A, Rusten TE, Stenmark H, Wesche J. Oppelt A, et al. EMBO Rep. 2013 Jan;14(1):57-64. doi: 10.1038/embor.2012.183. Epub 2012 Nov 16. EMBO Rep. 2013. PMID: 23154468 Free PMC article.

6

PIKfyve and its Lipid products in health and in sickness.

Shisheva A. Shisheva A. Curr Top Microbiol Immunol. 2012;362:127-62. doi: 10.1007/978-94-007-5025-8_7. Curr Top Microbiol Immunol. 2012. PMID: 23086417 Review.

7

In vivo, Pikfyve generates PI(3,5)P2, which serves as both a signaling lipid and the major precursor for PI5P.

Zolov SN, Bridges D, Zhang Y, Lee WW, Riehle E, Verma R, Lenk GM, Converso-Baran K, Weide T, Albin RL, Saltiel AR, Meisler MH, Russell MW, Weisman LS. Zolov SN, et al. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17472-7. doi: 10.1073/pnas.1203106109. Epub 2012 Oct 9. Proc Natl Acad Sci U S A. 2012. PMID: 23047693 Free PMC article.

8

The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice.

Ikonomov OC, Sbrissa D, Delvecchio K, Xie Y, Jin JP, Rappolee D, Shisheva A. Ikonomov OC, et al. J Biol Chem. 2011 Apr 15;286(15):13404-13. doi: 10.1074/jbc.M111.222364. Epub 2011 Feb 24. J Biol Chem. 2011. PMID: 21349843 Free PMC article.

9

ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder.

Ikonomov OC, Sbrissa D, Fligger J, Delvecchio K, Shisheva A. Ikonomov OC, et al. J Biol Chem. 2010 Aug 27;285(35):26760-26764. doi: 10.1074/jbc.C110.154658. Epub 2010 Jul 14. J Biol Chem. 2010. PMID: 20630877 Free PMC article.

10

Regulation of the glutamate transporter EAAT4 by PIKfyve.

Alesutan IS, Ureche ON, Laufer J, Klaus F, Zürn A, Lindner R, Strutz-Seebohm N, Tavaré JM, Boehmer C, Palmada M, Lang UE, Seebohm G, Lang F. Alesutan IS, et al. Cell Physiol Biochem. 2010;25(2-3):187-94. doi: 10.1159/000276569. Epub 2010 Jan 12. Cell Physiol Biochem. 2010. PMID: 20110679 Free article.

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