miR-128 represses L1 retrotransposition by binding directly to L1 RNA.
Nat Struct Mol Biol. 2015.
PMID: 26367248
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miR-128 represses L1 retrotransposition by binding directly to L1 RNA.
Hamdorf M, Idica A, Zisoulis DG, Gamelin L, Martin C, Sanders KJ, Pedersen IM.
Hamdorf M, et al.
Nat Struct Mol Biol. 2015 Oct;22(10):824-31. doi: 10.1038/nsmb.3090. Epub 2015 Sep 14.
Nat Struct Mol Biol. 2015.
PMID: 26367248
Long interspersed element 1 (LINE-1 or L1) retrotransposons compose 17% of the human genome. Active L1 elements are capable of replicative transposition (mobilization) and can act as drivers of genetic diversity. ...Here we show that miR-128 repress …
Long interspersed element 1 (LINE-1 or L1) retrotransposons compose 17% of the human genome. Active L1 elements are capable of …
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MicroRNA miR-128 represses LINE-1 (L1) retrotransposition by down-regulating the nuclear import factor TNPO1.
Idica A, Sevrioukov EA, Zisoulis DG, Hamdorf M, Daugaard I, Kadandale P, Pedersen IM.
Idica A, et al.
J Biol Chem. 2017 Dec 15;292(50):20494-20508. doi: 10.1074/jbc.M117.807677. Epub 2017 Oct 3.
J Biol Chem. 2017.
PMID: 28974576
Free PMC article.
We recently demonstrated that the microRNA miR-128 represses L1 activity by directly binding to L1 ORF2 RNA. In this study, we tested whether miR-128 can also control L1 activity by repressing cel …
We recently demonstrated that the microRNA miR-128 represses L1 activity by directly binding to …
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