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The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition.
Moldovan JB, Moran JV. Moldovan JB, et al. PLoS Genet. 2015 May 7;11(5):e1005121. doi: 10.1371/journal.pgen.1005121. eCollection 2015 May. PLoS Genet. 2015. PMID: 25951186 Free PMC article.
We identified 39 ORF1p-interacting candidate proteins including the zinc-finger antiviral protein (ZAP or ZC3HAV1). ...Together, these data suggest that ZAP inhibits the retrotransposition of LINE and Alu
We identified 39 ORF1p-interacting candidate proteins including the zinc-finger antiviral protein (ZAP
Riplet Binds the Zinc Finger Antiviral Protein (ZAP) and Augments ZAP-Mediated Restriction of HIV-1.
Buckmaster MV, Goff SP. Buckmaster MV, et al. J Virol. 2022 Aug 24;96(16):e0052622. doi: 10.1128/jvi.00526-22. Epub 2022 Aug 1. J Virol. 2022. PMID: 35913217 Free PMC article.
The zinc finger antiviral protein (ZAP) is an interferon-stimulated gene (ISG) with potent intrinsic antiviral activity. ZAP inhibits the replication of retroviruses, including murine leukemia virus (MLV) and HIV-1, as well …
The zinc finger antiviral protein (ZAP) is an interferon-stimulated gene (ISG) with potent intrinsic a