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Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact.
J Exp Med. 1997 Dec 15;186(12):2051-6. doi: 10.1084/jem.186.12.2051.
J Exp Med. 1997.
PMID: 9396775
Free PMC article.
Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection.
Jack RS, Fan X, Bernheiden M, Rune G, Ehlers M, Weber A, Kirsch G, Mentel R, Fürll B, Freudenberg M, Schmitz G, Stelter F, Schütt C.
Jack RS, et al.
Nature. 1997 Oct 16;389(6652):742-5. doi: 10.1038/39622.
Nature. 1997.
PMID: 9338787
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