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Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes.
Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1774-8. doi: 10.1073/pnas.92.5.1774.
Proc Natl Acad Sci U S A. 1995.
PMID: 7878058
Free PMC article.
Dual mechanisms for the low plasma levels of truncated apolipoprotein B proteins in familial hypobetalipoproteinemia. Analysis of a new mouse model with a nonsense mutation in the Apob gene.
Kim E, Cham CM, Véniant MM, Ambroziak P, Young SG.
Kim E, et al.
J Clin Invest. 1998 Mar 15;101(6):1468-77.
J Clin Invest. 1998.
PMID: 9502790
Free PMC article.
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