Fibrinolytic niche is required for alveolar type 2 cell-mediated alveologenesis via a uPA-A6-CD44⁺-ENaC signal cascade

Affiliations

• ¹ Department of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, TX, USA.
• ² Institute of Lung and Molecular Therapy, Xinxiang Medical University, Xinxiang, Henan, China.
• ³ Institute of Health Sciences, China Medical University, Shenyang, Liaoning, China.
• ⁴ Division of Pulmonary, Critical Care and Sleep Medicine, University of Southern California, Los Angeles, CA, USA.
• ⁵ Hastings Center for Pulmonary Research, University of Southern California, Los Angeles, CA, USA.
• ⁶ Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.
• ⁷ Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
• ⁸ Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
• ⁹ Department of Medicine and Anesthesia, University of California San Francisco, San Francisco, CA, USA.
• ¹⁰ Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, USA.
• ¹¹ Department of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, TX, USA. James.Ji@uthct.edu.
• ¹² Texas Lung Injury Institute, University of Texas Health Science Center at Tyler, Tyler, TX, USA. James.Ji@uthct.edu.