MAP9/ERCC3 signaling cascade: A new insight on understanding the chromosomal instability in hepatocellular carcinoma

EBioMedicine. 2020 Apr:54:102709. doi: 10.1016/j.ebiom.2020.102709. Epub 2020 Apr 5.

Authors

Etienne Ho Kit Mok¹, Carmen Oi Ning Leung¹, Terence Kin Wah Lee²

Affiliations

¹ Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University.
² Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University; State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong. Electronic address: terence.kw.lee@polyu.edu.hk.

No abstract available

MeSH terms

Animals
Carcinoma, Hepatocellular / genetics*
Carcinoma, Hepatocellular / metabolism
Carcinoma, Hepatocellular / pathology
Chromosomal Instability*
DNA Helicases / genetics*
DNA Helicases / metabolism
DNA Repair
DNA-Binding Proteins / genetics*
DNA-Binding Proteins / metabolism
Gene Expression Regulation, Neoplastic*
Humans
Liver Neoplasms / genetics*
Liver Neoplasms / metabolism
Liver Neoplasms / pathology
Mice
Mice, Knockout
Microtubule-Associated Proteins / deficiency
Microtubule-Associated Proteins / genetics*
Microtubule-Associated Proteins / metabolism
Signal Transduction
Tumor Suppressor Protein p53 / genetics
Tumor Suppressor Protein p53 / metabolism

Substances

DNA-Binding Proteins
MAP9 protein, human
Map9 protein, mouse
Microtubule-Associated Proteins
Tumor Suppressor Protein p53
XPBC-ERCC-3 protein
DNA Helicases