Epidemiology of Hepatic Encephalopathy

Mohamed I Elsaid; Vinod K Rustgi

doi:10.1016/j.cld.2020.01.001

Epidemiology of Hepatic Encephalopathy

Clin Liver Dis. 2020 May;24(2):157-174. doi: 10.1016/j.cld.2020.01.001. Epub 2020 Mar 2.

Authors

Mohamed I Elsaid¹, Vinod K Rustgi²

Affiliations

¹ Department of Medicine, Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, Medical Education Building, 1 Robert Wood Johnson, Room 479, New Brunswick, NJ 08903, USA. Electronic address: mie10@sph.rutgers.edu.
² Center for Liver Diseases and Liver Masses, Robert Wood Johnson School of Medicine, MedEd Building, Room 466, 1 Robert Wood Johnson Place, New Brunswick, NJ 08901, USA.

PMID: 32245524
DOI: 10.1016/j.cld.2020.01.001

Abstract

Hepatic encephalopathy (HE) is a complex condition with multiple causes each with varying degrees of severity. HE negatively impacts patients' quality of life, and it is associated with significant burdens to patients and their caregivers. The prevalence of cirrhosis, the most common risk factor for HE, has steadily increased during recent years. In turn, an upsurge in the clinical and health care burdens related to HE is expected in the upcoming years. This article provides a comprehensive review of the epidemiology of HE.

Keywords: Disease classification; Hepatic encephalopathy; Incidence; Prevalence; Prevention; Risk factors.

Publication types

Review

MeSH terms

Hepatic Encephalopathy / classification
Hepatic Encephalopathy / epidemiology*
Hepatic Encephalopathy / etiology*
Hepatic Encephalopathy / prevention & control
Humans
Incidence
Liver Cirrhosis / complications
Portasystemic Shunt, Transjugular Intrahepatic / adverse effects
Prevalence
Risk Factors
Survival Rate