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Mice with GNAO1 R209H Movement Disorder Variant Display Hyperlocomotion Alleviated by Risperidone.
J Pharmacol Exp Ther. 2020 Apr;373(1):24-33. doi: 10.1124/jpet.119.262733. Epub 2020 Jan 6.
J Pharmacol Exp Ther. 2020.
PMID: 31907305
Mouse models characterize GNAO1 encephalopathy as a neurodevelopmental disorder leading to motor anomalies: from a severe G203R to a milder C215Y mutation.
Silachev D, Koval A, Savitsky M, Padmasola G, Quairiaux C, Thorel F, Katanaev VL.
Silachev D, et al.
Acta Neuropathol Commun. 2022 Jan 28;10(1):9. doi: 10.1186/s40478-022-01312-z.
Acta Neuropathol Commun. 2022.
PMID: 35090564
Free PMC article.
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