Genetic Deletion of Semaphorin 3E Aggravates Airway Contraction in a Mouse Model of Allergic Asthma

Am J Respir Cell Mol Biol. 2019 May;60(5):601-603. doi: 10.1165/rcmb.2017-0434LE.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Intranasal
  • Animals
  • Asthma / chemically induced
  • Asthma / genetics*
  • Asthma / metabolism
  • Asthma / pathology
  • Bronchoconstriction / drug effects*
  • Cytoskeletal Proteins / deficiency
  • Cytoskeletal Proteins / genetics*
  • Cytoskeletal Proteins / pharmacology
  • Disease Models, Animal
  • Gene Deletion*
  • Gene Expression
  • Lung / drug effects
  • Lung / metabolism
  • Lung / pathology
  • Membrane Proteins / deficiency
  • Membrane Proteins / genetics*
  • Membrane Proteins / pharmacology
  • Methacholine Chloride / administration & dosage
  • Mice
  • Mice, Knockout
  • Microtomy
  • Pyroglyphidae / chemistry
  • Pyroglyphidae / immunology*
  • Recombinant Proteins / genetics
  • Recombinant Proteins / metabolism
  • Recombinant Proteins / pharmacology
  • Semaphorins
  • Signal Transduction

Substances

  • Cytoskeletal Proteins
  • Membrane Proteins
  • Recombinant Proteins
  • Sema3e protein, mouse
  • Semaphorins
  • Methacholine Chloride

Grants and funding