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Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load.
J Clin Invest. 2018 Aug 31;128(9):4179-4191. doi: 10.1172/JCI122095. Epub 2018 Aug 20.
J Clin Invest. 2018.
PMID: 30124468
Free PMC article.
DNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.
Albertson TM, Ogawa M, Bugni JM, Hays LE, Chen Y, Wang Y, Treuting PM, Heddle JA, Goldsby RE, Preston BD.
Albertson TM, et al.
Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17101-4. doi: 10.1073/pnas.0907147106. Epub 2009 Sep 24.
Proc Natl Acad Sci U S A. 2009.
PMID: 19805137
Free PMC article.
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