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Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal.
Sci Rep. 2018 Jan 11;8(1):425. doi: 10.1038/s41598-017-18828-3.
Sci Rep. 2018.
PMID: 29323231
Free PMC article.
Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs.
Minton DR, Nam M, McLaughlin DJ, Shin J, Bayraktar EC, Alvarez SW, Sviderskiy VO, Papagiannakopoulos T, Sabatini DM, Birsoy K, Possemato R.
Minton DR, et al.
Mol Cell. 2018 Feb 15;69(4):610-621.e5. doi: 10.1016/j.molcel.2018.01.024.
Mol Cell. 2018.
PMID: 29452640
Free PMC article.
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