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Leucine-rich repeat kinase 2 exacerbates neuronal cytotoxicity through phosphorylation of histone deacetylase 3 and histone deacetylation.
Hum Mol Genet. 2017 Jan 1;26(1):1-18. doi: 10.1093/hmg/ddw363.
Hum Mol Genet. 2017.
PMID: 27798112
Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.
Chen ZC, Zhang W, Chua LL, Chai C, Li R, Lin L, Cao Z, Angeles DC, Stanton LW, Peng JH, Zhou ZD, Lim KL, Zeng L, Tan EK.
Chen ZC, et al.
Sci Signal. 2017 Jul 18;10(488):eaam6790. doi: 10.1126/scisignal.aam6790.
Sci Signal. 2017.
PMID: 28720718
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