Abstract
Three chemically unrelated peroxidizing molecules, namely oxadiazon [5-(t-butyl)-3-(2,4-dichloro-5-isopropoxyphenyl)-1,3,4-oxadiazol-2 -one], LS 82-556 [(S)3-N-(methylbenzyl)carbamoyl-5-propionyl-2,6-lutidine] and M&B 39279 [5-amino-4-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazol], are potent inhibitors of plant, yeast and mouse protoporphyrinogen oxidase.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Chloroplasts / enzymology
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Flavoproteins
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Herbicides / pharmacology
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Mice
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Mice, Inbred DBA
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Mitochondria / enzymology
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Mitochondria, Liver / enzymology
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Mitochondrial Proteins
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Niacinamide / analogs & derivatives*
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Niacinamide / pharmacology
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Oxadiazoles / pharmacology*
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Oxidoreductases / antagonists & inhibitors*
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Oxidoreductases Acting on CH-CH Group Donors*
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Plants / enzymology
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Protoporphyrinogen Oxidase
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Pyrazoles / pharmacology*
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Saccharomyces cerevisiae / enzymology
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Solanum tuberosum
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Zea mays
Substances
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Flavoproteins
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Herbicides
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Mitochondrial Proteins
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Oxadiazoles
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Pyrazoles
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M&B 39279
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Niacinamide
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LS 82-556
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oxadiazon
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Oxidoreductases
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Oxidoreductases Acting on CH-CH Group Donors
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Ppox protein, mouse
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Protoporphyrinogen Oxidase