Abstract
Palmitoylation, the attachment of palmitate and other fatty acids on to cysteine residues, is a common post-translational modification of both integral and peripheral membrane proteins. Dynamic palmitoylation controls the intracellular distribution of peripheral membrane proteins by regulating membrane-cytosol exchange and/or by modifying the flux of the proteins through vesicular transport systems.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Membrane / metabolism
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Golgi Apparatus / metabolism
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Lipoylation*
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Membrane Proteins / metabolism*
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Palmitic Acid / metabolism*
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Protein Transport
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Subcellular Fractions
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Synaptosomal-Associated Protein 25 / metabolism
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ras Proteins / metabolism
Substances
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Membrane Proteins
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Synaptosomal-Associated Protein 25
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Palmitic Acid
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ras Proteins