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2009 | 1 |
2010 | 1 |
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APPL1 counteracts obesity-induced vascular insulin resistance and endothelial dysfunction by modulating the endothelial production of nitric oxide and endothelin-1 in mice.
Diabetes. 2011 Nov;60(11):3044-54. doi: 10.2337/db11-0666. Epub 2011 Sep 16.
Diabetes. 2011.
PMID: 21926268
Free PMC article.
Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts.
Tan Y, You H, Wu C, Altomare DA, Testa JR.
Tan Y, et al.
J Biol Chem. 2010 Feb 26;285(9):6377-89. doi: 10.1074/jbc.M109.068452. Epub 2009 Dec 29.
J Biol Chem. 2010.
PMID: 20040596
Free PMC article.
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Adaptor protein APPL1 coordinates HDAC3 to modulate brown adipose tissue thermogenesis in mice.
Fan L, Ye H, Wan Y, Qin L, Zhu L, Su J, Zhu X, Zhang L, Miao Q, Zhang Q, Zhang Z, Xu A, Li Y, Li X, Wang Y.
Fan L, et al.
Metabolism. 2019 Nov;100:153955. doi: 10.1016/j.metabol.2019.153955. Epub 2019 Aug 4.
Metabolism. 2019.
PMID: 31390528
Free article.
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