Abstract
We report an adolescent male with X-linked agammaglobulinemia (XLA) and recurrent episodes of pyogenic meningitis. The workup for proportionate short stature revealed isolated growth hormone deficiency. This patient highlights the delayed presentation of the XLA variant and the need to consider primary immunodeficiency in patients with recurrent serious infections, irrespective of age.
MeSH terms
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Adolescent
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Agammaglobulinemia / complications*
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Agammaglobulinemia / genetics*
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Anti-Bacterial Agents / therapeutic use
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Blood Protein Electrophoresis
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Body Height
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Genetic Diseases, X-Linked / complications*
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Genetic Diseases, X-Linked / genetics*
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Human Growth Hormone / deficiency*
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Humans
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Lymphocyte Count
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Male
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Meningitis / etiology
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Meningitis / immunology
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Meningitis / pathology*
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Recurrence
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Vomiting / complications
Substances
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Anti-Bacterial Agents
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Human Growth Hormone
Supplementary concepts
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Bruton type agammaglobulinemia