Controversies in ocular toxoplasmosis

Ocul Immunol Inflamm. 2011 Feb;19(1):2-9. doi: 10.3109/09273948.2011.547157.

Abstract

Toxoplasmosis, a major cause of infectious uveitis, was elected by the editors of Ocular Immunology and Inflammation as the disease of the year for 2011. The aim of the present review was to report on the results of a survey of leading uveitis experts, in which the authors asked participants to address some of the most important issues related to diagnosis, pathophysiology, and treatment of ocular toxoplasmosis. The survey revealed generally good consensus regarding clinical signs of typical and atypical toxoplasmic retinochoroiditis. In contrast, views regarding diagnostic approach, possible epidemiological influences, transmission of disease, and trigger factors seemed less clearly defined. Responses revealed a large number of drug regimens in use for both congenital and acquired disease. Finally, recurrence prophylaxis was not regularly recommended by the majority of experts.

Publication types

  • Review

MeSH terms

  • Antiprotozoal Agents / therapeutic use
  • Chorioretinitis / diagnosis*
  • Chorioretinitis / drug therapy
  • Chorioretinitis / parasitology*
  • Chorioretinitis / physiopathology
  • Female
  • Humans
  • Recurrence
  • Toxoplasmosis, Ocular / complications*
  • Toxoplasmosis, Ocular / diagnosis*
  • Toxoplasmosis, Ocular / drug therapy
  • Toxoplasmosis, Ocular / physiopathology
  • Toxoplasmosis, Ocular / transmission

Substances

  • Antiprotozoal Agents