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HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide.
Nat Immunol. 2011 Jan;12(1):54-61. doi: 10.1038/ni.1967. Epub 2010 Dec 5.
Nat Immunol. 2011.
PMID: 21131964
Free PMC article.
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism.
Guce AI, Mortimer SE, Yoon T, Painter CA, Jiang W, Mellins ED, Stern LJ.
Guce AI, et al.
Nat Struct Mol Biol. 2013 Jan;20(1):90-8. doi: 10.1038/nsmb.2460. Epub 2012 Dec 9.
Nat Struct Mol Biol. 2013.
PMID: 23222639
Free PMC article.
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