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Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps.
J Biol Chem. 2011 Jan 14;286(2):1292-300. doi: 10.1074/jbc.M110.154849. Epub 2010 Nov 9.
J Biol Chem. 2011.
PMID: 21062743
Free PMC article.
EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step.
Ninagawa S, Okada T, Sumitomo Y, Kamiya Y, Kato K, Horimoto S, Ishikawa T, Takeda S, Sakuma T, Yamamoto T, Mori K.
Ninagawa S, et al.
J Cell Biol. 2014 Aug 4;206(3):347-56. doi: 10.1083/jcb.201404075.
J Cell Biol. 2014.
PMID: 25092655
Free PMC article.
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