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ADAMTS-5 deficient mice do not develop mechanical allodynia associated with osteoarthritis following medial meniscal destabilization.
Osteoarthritis Cartilage. 2010 Apr;18(4):572-80. doi: 10.1016/j.joca.2009.11.013. Epub 2009 Dec 21.
Osteoarthritis Cartilage. 2010.
PMID: 20036347
Free article.
ADAMTS-5 deficiency does not block aggrecanolysis at preferred cleavage sites in the chondroitin sulfate-rich region of aggrecan.
East CJ, Stanton H, Golub SB, Rogerson FM, Fosang AJ.
East CJ, et al.
J Biol Chem. 2007 Mar 23;282(12):8632-40. doi: 10.1074/jbc.M605750200. Epub 2007 Jan 25.
J Biol Chem. 2007.
PMID: 17255106
Free article.
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Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis.
Glasson SS, Askew R, Sheppard B, Carito B, Blanchet T, Ma HL, Flannery CR, Peluso D, Kanki K, Yang Z, Majumdar MK, Morris EA.
Glasson SS, et al.
Nature. 2005 Mar 31;434(7033):644-8. doi: 10.1038/nature03369.
Nature. 2005.
PMID: 15800624
Free article.
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ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro.
Stanton H, Rogerson FM, East CJ, Golub SB, Lawlor KE, Meeker CT, Little CB, Last K, Farmer PJ, Campbell IK, Fourie AM, Fosang AJ.
Stanton H, et al.
Nature. 2005 Mar 31;434(7033):648-52. doi: 10.1038/nature03417.
Nature. 2005.
PMID: 15800625
Free article.
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