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Year | Number of Results |
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2009 | 2 |
2013 | 1 |
2018 | 1 |
2024 | 0 |
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Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.
Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14872-7. doi: 10.1073/pnas.0906587106. Epub 2009 Aug 18.
Proc Natl Acad Sci U S A. 2009.
PMID: 19706465
Free PMC article.
Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity.
Kleiner S, Gomez D, Megra B, Na E, Bhavsar R, Cavino K, Xin Y, Rojas J, Dominguez-Gutierrez G, Zambrowicz B, Carrat G, Chabosseau P, Hu M, Murphy AJ, Yancopoulos GD, Rutter GA, Gromada J.
Kleiner S, et al.
Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):E7642-E7649. doi: 10.1073/pnas.1721418115. Epub 2018 Jul 23.
Proc Natl Acad Sci U S A. 2018.
PMID: 30038024
Free PMC article.
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Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion.
Pound LD, Sarkar SA, Benninger RK, Wang Y, Suwanichkul A, Shadoan MK, Printz RL, Oeser JK, Lee CE, Piston DW, McGuinness OP, Hutton JC, Powell DR, O'Brien RM.
Pound LD, et al.
Biochem J. 2009 Jul 15;421(3):371-6. doi: 10.1042/BJ20090530.
Biochem J. 2009.
PMID: 19450229
Free PMC article.
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The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance.
Tamaki M, Fujitani Y, Hara A, Uchida T, Tamura Y, Takeno K, Kawaguchi M, Watanabe T, Ogihara T, Fukunaka A, Shimizu T, Mita T, Kanazawa A, Imaizumi MO, Abe T, Kiyonari H, Hojyo S, Fukada T, Kawauchi T, Nagamatsu S, Hirano T, Kawamori R, Watada H.
Tamaki M, et al.
J Clin Invest. 2013 Oct;123(10):4513-24. doi: 10.1172/JCI68807. Epub 2013 Sep 24.
J Clin Invest. 2013.
PMID: 24051378
Free PMC article.
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