Phage display derived therapeutic antibodies

Curr Pharm Biotechnol. 2008 Dec;9(6):439-46. doi: 10.2174/138920108786786349.

Abstract

This article gives an overview about the development of human therapeutic antibodies generated by phage display. After an introduction to the method, the focus is on approved antibodies and those currently in clinical trials, 14 of which are described in detail.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antibodies, Monoclonal / therapeutic use*
  • Drug Design*
  • Humans
  • Immunotherapy / methods*
  • Immunotherapy / trends*
  • Peptide Library
  • Protein Engineering / trends*

Substances

  • Antibodies, Monoclonal
  • Peptide Library