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Mutant Lrp1 knock-in mice generated by recombinase-mediated cassette exchange reveal differential importance of the NPXY motifs in the intracellular domain of LRP1 for normal fetal development.
Mol Cell Biol. 2006 Jan;26(2):605-16. doi: 10.1128/MCB.26.2.605-616.2006.
Mol Cell Biol. 2006.
PMID: 16382151
Free PMC article.
Sustained somatic gene inactivation by viral transfer of Cre recombinase.
Rohlmann A, Gotthardt M, Willnow TE, Hammer RE, Herz J.
Rohlmann A, et al.
Nat Biotechnol. 1996 Nov;14(11):1562-5. doi: 10.1038/nbt1196-1562.
Nat Biotechnol. 1996.
PMID: 9634821
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LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation.
Herz J, Clouthier DE, Hammer RE.
Herz J, et al.
Cell. 1992 Oct 30;71(3):411-21. doi: 10.1016/0092-8674(92)90511-a.
Cell. 1992.
PMID: 1423604
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Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis.
Reekmans SM, Pflanzner T, Gordts PL, Isbert S, Zimmermann P, Annaert W, Weggen S, Roebroek AJ, Pietrzik CU.
Reekmans SM, et al.
Cell Mol Life Sci. 2010 Jan;67(1):135-45. doi: 10.1007/s00018-009-0171-7. Epub 2009 Oct 25.
Cell Mol Life Sci. 2010.
PMID: 19856143
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