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Disruption of caveolin-1 leads to enhanced nitrosative stress and severe systolic and diastolic heart failure.
Biochem Biophys Res Commun. 2006 Feb 10;340(2):702-8. doi: 10.1016/j.bbrc.2005.12.058. Epub 2005 Dec 20.
Biochem Biophys Res Commun. 2006.
PMID: 16380094
Nitric oxide synthases are crucially involved in the development of the severe cardiomyopathy of caveolin-1 knockout mice.
Wunderlich C, Schober K, Kasper M, Heerwagen C, Marquetant R, Ebner B, Forkmann M, Schoen S, Braun-Dullaeus RC, Schmeisser A, Strasser RH.
Wunderlich C, et al.
Biochem Biophys Res Commun. 2008 Dec 19;377(3):769-74. doi: 10.1016/j.bbrc.2008.10.068. Epub 2008 Oct 23.
Biochem Biophys Res Commun. 2008.
PMID: 18951881
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