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The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis.
Hum Mol Genet. 2005 May 1;14(9):1231-41. doi: 10.1093/hmg/ddi134. Epub 2005 Mar 24.
Hum Mol Genet. 2005.
PMID: 15790595
DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor.
Zhong N, Kim CY, Rizzu P, Geula C, Porter DR, Pothos EN, Squitieri F, Heutink P, Xu J.
Zhong N, et al.
J Biol Chem. 2006 Jul 28;281(30):20940-20948. doi: 10.1074/jbc.M601935200. Epub 2006 May 26.
J Biol Chem. 2006.
PMID: 16731528
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