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Axin contains three separable domains that confer intramolecular, homodimeric, and heterodimeric interactions involved in distinct functions.
J Biol Chem. 2005 Feb 11;280(6):5054-60. doi: 10.1074/jbc.M412340200. Epub 2004 Dec 5.
J Biol Chem. 2005.
PMID: 15579909
Free article.
Both the RGS domain and the six C-terminal amino acids of mouse Axin are required for normal embryogenesis.
Chia IV, Kim MJ, Itoh K, Sokol SY, Costantini F.
Chia IV, et al.
Genetics. 2009 Apr;181(4):1359-68. doi: 10.1534/genetics.109.101055. Epub 2009 Feb 9.
Genetics. 2009.
PMID: 19204372
Free PMC article.
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