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Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit.
Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):7041-5. doi: 10.1073/pnas.89.15.7041.
Proc Natl Acad Sci U S A. 1992.
PMID: 1495999
Free PMC article.
JAK2 and JAK1 constitutively associate with an interleukin-5 (IL-5) receptor alpha and betac subunit, respectively, and are activated upon IL-5 stimulation.
Ogata N, Kouro T, Yamada A, Koike M, Hanai N, Ishikawa T, Takatsu K.
Ogata N, et al.
Blood. 1998 Apr 1;91(7):2264-71.
Blood. 1998.
PMID: 9516124
Free article.
Item in Clipboard
Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch.
Guthridge MA, Powell JA, Barry EF, Stomski FC, McClure BJ, Ramshaw H, Felquer FA, Dottore M, Thomas DT, To B, Begley CG, Lopez AF.
Guthridge MA, et al.
EMBO J. 2006 Feb 8;25(3):479-89. doi: 10.1038/sj.emboj.7600948. Epub 2006 Jan 26.
EMBO J. 2006.
PMID: 16437163
Free PMC article.
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CBAP interacts with the un-liganded common beta-subunit of the GM-CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial dysfunction.
Kao CJ, Chiang YJ, Chen PH, Lin KR, Hwang PI, Yang-Yen HF, Yen JJ.
Kao CJ, et al.
Oncogene. 2008 Feb 28;27(10):1397-403. doi: 10.1038/sj.onc.1210778. Epub 2007 Sep 10.
Oncogene. 2008.
PMID: 17828305
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The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation.
Hansen G, Hercus TR, McClure BJ, Stomski FC, Dottore M, Powell J, Ramshaw H, Woodcock JM, Xu Y, Guthridge M, McKinstry WJ, Lopez AF, Parker MW.
Hansen G, et al.
Cell. 2008 Aug 8;134(3):496-507. doi: 10.1016/j.cell.2008.05.053.
Cell. 2008.
PMID: 18692472
Free article.
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Inhibition of β1 integrin and IL-3Rβ common subunit interaction hinders tumour angiogenesis.
Uberti B, Dentelli P, Rosso A, Defilippi P, Brizzi MF.
Uberti B, et al.
Oncogene. 2010 Dec 16;29(50):6581-90. doi: 10.1038/onc.2010.384. Epub 2010 Aug 30.
Oncogene. 2010.
PMID: 20802515
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A dual role for the N-terminal domain of the IL-3 receptor in cell signalling.
Broughton SE, Hercus TR, Nero TL, Kan WL, Barry EF, Dottore M, Cheung Tung Shing KS, Morton CJ, Dhagat U, Hardy MP, Wilson NJ, Downton MT, Schieber C, Hughes TP, Lopez AF, Parker MW.
Broughton SE, et al.
Nat Commun. 2018 Jan 26;9(1):386. doi: 10.1038/s41467-017-02633-7.
Nat Commun. 2018.
PMID: 29374162
Free PMC article.
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