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Year | Number of Results |
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2003 | 1 |
2011 | 1 |
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Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis.
Mol Cell. 2003 Mar;11(3):591-604. doi: 10.1016/s1097-2765(03)00056-x.
Mol Cell. 2003.
PMID: 12667444
Free article.
Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels.
Hesker PR, Nguyen M, Kovarova M, Ting JP, Koller BH.
Hesker PR, et al.
PLoS One. 2012;7(11):e51105. doi: 10.1371/journal.pone.0051105. Epub 2012 Nov 30.
PLoS One. 2012.
PMID: 23226472
Free PMC article.
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Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation.
Van Gorp H, Saavedra PH, de Vasconcelos NM, Van Opdenbosch N, Vande Walle L, Matusiak M, Prencipe G, Insalaco A, Van Hauwermeiren F, Demon D, Bogaert DJ, Dullaers M, De Baere E, Hochepied T, Dehoorne J, Vermaelen KY, Haerynck F, De Benedetti F, Lamkanfi M.
Van Gorp H, et al.
Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):14384-14389. doi: 10.1073/pnas.1613156113. Epub 2016 Nov 22.
Proc Natl Acad Sci U S A. 2016.
PMID: 27911804
Free PMC article.
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Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice.
Chae JJ, Cho YH, Lee GS, Cheng J, Liu PP, Feigenbaum L, Katz SI, Kastner DL.
Chae JJ, et al.
Immunity. 2011 May 27;34(5):755-68. doi: 10.1016/j.immuni.2011.02.020. Epub 2011 May 19.
Immunity. 2011.
PMID: 21600797
Free PMC article.
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