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Constitutive knockout of Surf1 is associated with high embryonic lethality, mitochondrial disease and cytochrome c oxidase deficiency in mice.
Hum Mol Genet. 2003 Feb 15;12(4):399-413. doi: 10.1093/hmg/ddg038.
Hum Mol Genet. 2003.
PMID: 12566387
Decreased in vitro mitochondrial function is associated with enhanced brain metabolism, blood flow, and memory in Surf1-deficient mice.
Lin AL, Pulliam DA, Deepa SS, Halloran JJ, Hussong SA, Burbank RR, Bresnen A, Liu Y, Podlutskaya N, Soundararajan A, Muir E, Duong TQ, Bokov AF, Viscomi C, Zeviani M, Richardson AG, Van Remmen H, Fox PT, Galvan V.
Lin AL, et al.
J Cereb Blood Flow Metab. 2013 Oct;33(10):1605-11. doi: 10.1038/jcbfm.2013.116. Epub 2013 Jul 10.
J Cereb Blood Flow Metab. 2013.
PMID: 23838831
Free PMC article.
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