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Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans.
Nat Genet. 2002 Nov;32(3):359-69. doi: 10.1038/ng1009. Epub 2002 Oct 15.
Nat Genet. 2002.
PMID: 12379852
Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation.
Colombo E, Collombat P, Colasante G, Bianchi M, Long J, Mansouri A, Rubenstein JL, Broccoli V.
Colombo E, et al.
J Neurosci. 2007 Apr 25;27(17):4786-98. doi: 10.1523/JNEUROSCI.0417-07.2007.
J Neurosci. 2007.
PMID: 17460091
Free PMC article.
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