Pattern of expression of the tetraspanin Tspan-5 during brain development in the mouse

Mech Dev. 2001 Aug;106(1-2):207-12. doi: 10.1016/s0925-4773(01)00436-1.

Abstract

Here, we report the pattern of expression of the tetraspanin mTspan-5 at various developmental stages. Expression was first seen at E10 and remained until adulthood, with increased levels between P0 and P5. mTspan-5 showed high expression in the cortical areas and Purkinje cells throughout development. Moreover, transcripts were also detected in the developing heart, forelimbs, and hindlimbs.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Brain / embryology
  • Brain / growth & development
  • Brain / metabolism*
  • Cerebellum / embryology
  • Cerebellum / growth & development
  • Cerebellum / metabolism
  • Gene Expression Profiling
  • Gene Expression*
  • In Situ Hybridization
  • Membrane Proteins / genetics*
  • Mice
  • Prosencephalon / embryology
  • Prosencephalon / growth & development
  • Prosencephalon / metabolism
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Tetraspanins

Substances

  • Membrane Proteins
  • RNA, Messenger
  • Tetraspanins
  • Tspan5 protein, mouse