Abstract
Here, we report the pattern of expression of the tetraspanin mTspan-5 at various developmental stages. Expression was first seen at E10 and remained until adulthood, with increased levels between P0 and P5. mTspan-5 showed high expression in the cortical areas and Purkinje cells throughout development. Moreover, transcripts were also detected in the developing heart, forelimbs, and hindlimbs.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Brain / embryology
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Brain / growth & development
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Brain / metabolism*
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Cerebellum / embryology
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Cerebellum / growth & development
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Cerebellum / metabolism
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Gene Expression Profiling
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Gene Expression*
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In Situ Hybridization
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Membrane Proteins / genetics*
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Mice
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Prosencephalon / embryology
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Prosencephalon / growth & development
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Prosencephalon / metabolism
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RNA, Messenger / genetics
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RNA, Messenger / metabolism
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Tetraspanins
Substances
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Membrane Proteins
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RNA, Messenger
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Tetraspanins
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Tspan5 protein, mouse