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Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress.
Cancer Res. 2001 Jul 15;61(14):5552-7.
Cancer Res. 2001.
PMID: 11454706
Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding.
Ordway JM, Eberhart D, Curran T.
Ordway JM, et al.
Mol Cell Biol. 2003 Jun;23(12):4257-66. doi: 10.1128/MCB.23.12.4257-4266.2003.
Mol Cell Biol. 2003.
PMID: 12773568
Free PMC article.
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APE1/Ref-1 facilitates recovery of gray and white matter and neurological function after mild stroke injury.
Stetler RA, Gao Y, Leak RK, Weng Z, Shi Y, Zhang L, Pu H, Zhang F, Hu X, Hassan S, Ferguson C, Homanics GE, Cao G, Bennett MV, Chen J.
Stetler RA, et al.
Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):E3558-67. doi: 10.1073/pnas.1606226113. Epub 2016 Jun 6.
Proc Natl Acad Sci U S A. 2016.
PMID: 27274063
Free PMC article.
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Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors.
Dumitrache LC, Shimada M, Downing SM, Kwak YD, Li Y, Illuzzi JL, Russell HR, Wilson DM 3rd, McKinnon PJ.
Dumitrache LC, et al.
Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12285-E12294. doi: 10.1073/pnas.1809682115. Epub 2018 Dec 11.
Proc Natl Acad Sci U S A. 2018.
PMID: 30538199
Free PMC article.
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The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.
Xanthoudakis S, Smeyne RJ, Wallace JD, Curran T.
Xanthoudakis S, et al.
Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):8919-23. doi: 10.1073/pnas.93.17.8919.
Proc Natl Acad Sci U S A. 1996.
PMID: 8799128
Free PMC article.
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A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity.
Ludwig DL, MacInnes MA, Takiguchi Y, Purtymun PE, Henrie M, Flannery M, Meneses J, Pedersen RA, Chen DJ.
Ludwig DL, et al.
Mutat Res. 1998 Oct 21;409(1):17-29. doi: 10.1016/s0921-8777(98)00039-1.
Mutat Res. 1998.
PMID: 9806499
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