Abstract
A current paradigm has ICOS participating in TH2 costimulation. New data indicates ICOS regulates not only TH2 cells, but also TH1s.
MeSH terms
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Abatacept
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Animals
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Antigens, CD
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Antigens, Differentiation / immunology
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Antigens, Differentiation, T-Lymphocyte / immunology*
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CD40 Ligand / immunology
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CTLA-4 Antigen
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Cytokines / immunology
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DNA-Binding Proteins / immunology
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GATA3 Transcription Factor
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Heart Transplantation / immunology
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Immunoconjugates*
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Inducible T-Cell Co-Stimulator Protein
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Lymphocyte Activation / immunology
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Proto-Oncogene Proteins / immunology
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Proto-Oncogene Proteins c-maf
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Signal Transduction / immunology*
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Th1 Cells / immunology*
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Th2 Cells / immunology*
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Trans-Activators / immunology
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Transplantation, Homologous / immunology
Substances
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Antigens, CD
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Antigens, Differentiation
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Antigens, Differentiation, T-Lymphocyte
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CTLA-4 Antigen
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Cytokines
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DNA-Binding Proteins
-
GATA3 Transcription Factor
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Immunoconjugates
-
Inducible T-Cell Co-Stimulator Protein
-
Proto-Oncogene Proteins
-
Proto-Oncogene Proteins c-maf
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Trans-Activators
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CD40 Ligand
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Abatacept