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The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts.
J Biol Chem. 1999 Dec 24;274(52):37491-8. doi: 10.1074/jbc.274.52.37491.
J Biol Chem. 1999.
PMID: 10601325
Free article.
TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter.
Myhrstad MC, Husberg C, Murphy P, Nordström O, Blomhoff R, Moskaug JO, Kolstø AB.
Myhrstad MC, et al.
Biochim Biophys Acta. 2001 Jan 26;1517(2):212-9. doi: 10.1016/s0167-4781(00)00276-1.
Biochim Biophys Acta. 2001.
PMID: 11342101
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