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Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin.
J Immunol. 1999 Aug 15;163(4):1929-35.
J Immunol. 1999.
PMID: 10438928
The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor.
Barillari G, Sgadari C, Fiorelli V, Samaniego F, Colombini S, Manzari V, Modesti A, Nair BC, Cafaro A, Stürzl M, Ensoli B.
Barillari G, et al.
Blood. 1999 Jul 15;94(2):663-72.
Blood. 1999.
PMID: 10397733
Free article.
Item in Clipboard
Fibronectin modulates the effects of HIV-1 Tat on the growth of murine Kaposi's sarcoma-like cells through the down-regulation of tyrosine phosphorylation.
Wu Z, Cavallaro U, Marchisio PC, Soria MR, Maier JA.
Wu Z, et al.
Am J Pathol. 1998 Jun;152(6):1599-605.
Am J Pathol. 1998.
PMID: 9626063
Free PMC article.
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The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence.
Barillari G, Gendelman R, Gallo RC, Ensoli B.
Barillari G, et al.
Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):7941-5. doi: 10.1073/pnas.90.17.7941.
Proc Natl Acad Sci U S A. 1993.
PMID: 7690138
Free PMC article.
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Angiogenic properties of human immunodeficiency virus type 1 Tat protein.
Albini A, Barillari G, Benelli R, Gallo RC, Ensoli B.
Albini A, et al.
Proc Natl Acad Sci U S A. 1995 May 23;92(11):4838-42. doi: 10.1073/pnas.92.11.4838.
Proc Natl Acad Sci U S A. 1995.
PMID: 7539135
Free PMC article.
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