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The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway.
Nature. 1999 Mar 18;398(6724):252-6. doi: 10.1038/18465.
Nature. 1999.
PMID: 10094049
TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop.
Kishimoto K, Matsumoto K, Ninomiya-Tsuji J.
Kishimoto K, et al.
J Biol Chem. 2000 Mar 10;275(10):7359-64. doi: 10.1074/jbc.275.10.7359.
J Biol Chem. 2000.
PMID: 10702308
Free article.
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TAK1 is a ubiquitin-dependent kinase of MKK and IKK.
Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ.
Wang C, et al.
Nature. 2001 Jul 19;412(6844):346-51. doi: 10.1038/35085597.
Nature. 2001.
PMID: 11460167
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TAK1 is an essential kinase for STING trafficking.
Ma M, Dang Y, Chang B, Wang F, Xu J, Chen L, Su H, Li J, Ge B, Chen C, Liu H.
Ma M, et al.
Mol Cell. 2023 Nov 2;83(21):3885-3903.e5. doi: 10.1016/j.molcel.2023.09.009. Epub 2023 Oct 12.
Mol Cell. 2023.
PMID: 37832545
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