Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity.
Couturier C, Sarkis C, Séron K, Belouzard S, Chen P, Lenain A, Corset L, Dam J, Vauthier V, Dubart A, et al. Proc Natl Acad Sci U S A. 2007 Dec 4; 104(49):19476-81. Epub 2007 Nov 27.