In Semliki Forest virus encephalitis, suppressor of cytokine signaling 4 (SOCS4) is an essential modulator of immune responses that mediates the balance between immunopathology and virus clearance.
Kedzierski L, Er Qi Tan A, Jia Hui Foo I, Narayanan D, Moily N, McQuilten HA, Nicholson SE, Fazakerley JK. Immunol Cell Biol. 2023 Apr; 101(4):333-344. Epub 2023 Feb 14.