RecName: Full=Histone-lysine N-methyltransferase NSD2; AltName: Full=M - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Clinical details of individuals with Rauch-Steindl syndrome due to NSD2 truncating variants. [Mol Genet Genomic Med. 2024]
Clinical details of individuals with Rauch-Steindl syndrome due to NSD2 truncating variants.
Nishi E, Yanagi K, Kaname T, Okamoto N. Mol Genet Genomic Med. 2024 Feb; 12(2):e2396.
Decreased NSD2 impairs stromal cell proliferation in human endometrium via reprogramming H3K36me2. [Reproduction. 2024]
Decreased NSD2 impairs stromal cell proliferation in human endometrium via reprogramming H3K36me2.
Qin CM, Wei XW, Wu JY, Liu XQ, Lin Y. Reproduction. 2024 Mar 1; 167(3). Epub 2024 Feb 12.
The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation. [J Biol Chem. 2023]
The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation.
Khella MS, Schnee P, Weirich S, Bui T, Bröhm A, Bashtrykov P, Pleiss J, Jeltsch A. J Biol Chem. 2023 Jun; 299(6):104796. Epub 2023 May 5.

RefSeq genomic sequence
See the genomic reference sequence for the NSD2 gene (NG_009269.1).
RefSeq protein isoforms
See 29 reference sequence protein isoforms for the NSD2 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (List)
PubChem BioAssays done on the protein target
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
Related Structures (Summary)
Related structures

Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Histone-lysine N-methyltransferase NSD2; AltName: Full=Multiple my...
RecName: Full=Histone-lysine N-methyltransferase NSD2; AltName: Full=Multiple myeloma SET domain-containing protein; Short=MMSET; AltName: Full=Nuclear SET domain-containing protein 2; AltName: Full=Protein trithorax-5; AltName: Full=Wolf-Hirschhorn syndrome candidate 1 protein
gi|74706096|sp|O96028.1|NSD2_HUMAN

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein