RecName: Full=Aspartate aminotransferase, cytoplasmic; Short=cAspAT; A - Protein

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Tumor Cell Derived Exosomal GOT1 Suppresses Tumor Cell Ferroptosis to Accelerate Pancreatic Cancer Progression by Activating Nrf2/HO-1 Axis via Upregulating CCR2 Expression. [Cells. 2022]
Tumor Cell Derived Exosomal GOT1 Suppresses Tumor Cell Ferroptosis to Accelerate Pancreatic Cancer Progression by Activating Nrf2/HO-1 Axis via Upregulating CCR2 Expression.
Guo Y, Chen T, Liang X, Gou S, Xiong J, Cui J, Peng T. Cells. 2022 Dec 2; 11(23). Epub 2022 Dec 2.
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis. [Nat Commun. 2021]
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, et al. Nat Commun. 2021 Aug 11; 12(1):4860. Epub 2021 Aug 11.
Structural and functional analysis of disease-associated mutations in GOT1 gene: An in silico study. [Comput Biol Med. 2021]
Structural and functional analysis of disease-associated mutations in GOT1 gene: An in silico study.
Saxena S, Achyuth B S, Murthy TPK, Chandramohan V, Yadav AK, Singh TR. Comput Biol Med. 2021 Sep; 136:104695. Epub 2021 Jul 29.

RefSeq genomic sequence
See the genomic reference sequence for the GOT1 gene (NG_032044.1).
RefSeq protein
See the reference protein sequence for aspartate aminotransferase, cytoplasmic (NP_002070.1).

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P17174 [Domain Mapping of Disease Mut...]
P17174
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Aspartate aminotransferase, cytoplasmic; Short=cAspAT; AltName: Fu...
RecName: Full=Aspartate aminotransferase, cytoplasmic; Short=cAspAT; AltName: Full=Cysteine aminotransferase, cytoplasmic; AltName: Full=Cysteine transaminase, cytoplasmic; Short=cCAT; AltName: Full=Glutamate oxaloacetate transaminase 1; AltName: Full=Transaminase A
gi|5902703|sp|P17174.3|AATC_HUMAN

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