RecName: Full=Heterogeneous nuclear ribonucleoprotein A1; Short=hnRNP - Protein

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hnRNP A1 dysfunction alters RNA splicing and drives neurodegeneration in multiple sclerosis (MS). [Nat Commun. 2024]
hnRNP A1 dysfunction alters RNA splicing and drives neurodegeneration in multiple sclerosis (MS).
Salapa HE, Thibault PA, Libner CD, Ding Y, Clarke JWE, Denomy C, Hutchinson C, Abidullah HM, Austin Hammond S, Pastushok L, et al. Nat Commun. 2024 Jan 8; 15(1):356. Epub 2024 Jan 8.
A mutation in the low-complexity domain of splicing factor hnRNPA1 linked to amyotrophic lateral sclerosis disrupts distinct neuronal RNA splicing networks. [Genes Dev. 2024]
A mutation in the low-complexity domain of splicing factor hnRNPA1 linked to amyotrophic lateral sclerosis disrupts distinct neuronal RNA splicing networks.
Lee YJ, Rio DC. Genes Dev. 2024 Feb 13; 38(1-2):11-30. Epub 2024 Feb 13.
The mechanism of UP1 binding and unfolding of human telomeric DNA G-quadruplex. [Biochim Biophys Acta Gene Regu...]
The mechanism of UP1 binding and unfolding of human telomeric DNA G-quadruplex.
Ling X, Yao Y, Ding L, Ma J. Biochim Biophys Acta Gene Regul Mech. 2023 Dec; 1866(4):194985. Epub 2023 Sep 16.

RefSeq genomic sequence
See the genomic reference sequence for the HNRNPA1 gene (NG_033830.1).
RefSeq protein isoforms
See 2 reference sequence protein isoforms for the HNRNPA1 gene.

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P09651 [Domain Mapping of Disease Mut...]
P09651
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
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PANTHER Classification System
Reactome [Reactome]
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reagents [ExactAntigen/Labome]
reagents
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RecName: Full=Heterogeneous nuclear ribonucleoprotein A1; Short=hnRNP A1; AltNam...
RecName: Full=Heterogeneous nuclear ribonucleoprotein A1; Short=hnRNP A1; AltName: Full=Helix-destabilizing protein; AltName: Full=Single-strand RNA-binding protein; AltName: Full=hnRNP core protein A1; Contains: RecName: Full=Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed
gi|288558857|sp|P09651.5|ROA1_HUMAN

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