RecName: Full=Caspase recruitment domain-containing protein 8; AltName - Protein

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Association between C10X polymorphism in the CARD8 gene and inflammatory markers in young healthy individuals in the LBA study. [BMC Cardiovasc Disord. 2024]
Association between C10X polymorphism in the CARD8 gene and inflammatory markers in young healthy individuals in the LBA study.
Fransén K, Hiyoshi A, Paramel GV, Hurtig-Wennlöf A. BMC Cardiovasc Disord. 2024 Feb 13; 24(1):103. Epub 2024 Feb 13.
A human-specific motif facilitates CARD8 inflammasome activation after HIV-1 infection. [Elife. 2023]
A human-specific motif facilitates CARD8 inflammasome activation after HIV-1 infection.
Kulsuptrakul J, Turcotte EA, Emerman M, Mitchell PS. Elife. 2023 Jul 7; 12. Epub 2023 Jul 7.
A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome. [J Biol Chem. 2022]
A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome.
Hsiao JC, Neugroschl AR, Chui AJ, Taabazuing CY, Griswold AR, Wang Q, Huang HC, Orth-He EL, Ball DP, Hiotis G, et al. J Biol Chem. 2022 Jul; 298(7):102032. Epub 2022 May 14.

RefSeq genomic sequence
See the genomic reference sequence for the CARD8 gene (NG_029574.3).
RefSeq protein isoforms
See 104 reference sequence protein isoforms for the CARD8 gene.

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Q9Y2G2 [Domain Mapping of Disease Mut...]
Q9Y2G2
Domain Mapping of Disease Mutations
Reactome [Reactome]
Reactome

RecName: Full=Caspase recruitment domain-containing protein 8; AltName: Full=CAR...
RecName: Full=Caspase recruitment domain-containing protein 8; AltName: Full=CARD-inhibitor of NF-kappa-B-activating ligand; Short=CARDINAL; AltName: Full=Tumor up-regulated CARD-containing antagonist of CASP9; Short=TUCAN; Contains: RecName: Full=Caspase recruitment domain-containing protein 8, C-terminus; Short=CARD8-CT; Contains: RecName: Full=Caspase recruitment domain-containing protein 8, N-terminus; Short=CARD8-NT
gi|2055117251|sp|Q9Y2G2.2|CARD8_HUM

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