RecName: Full=Cleavage and polyadenylation specificity factor subunit - Protein

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CPSF3 inhibition blocks pancreatic cancer cell proliferation through disruption of core histone mRNA processing. [RNA. 2024]
CPSF3 inhibition blocks pancreatic cancer cell proliferation through disruption of core histone mRNA processing.
Alahmari AA, Chaubey AH, Jonnakuti VS, Tisdale AA, Schwarz CD, Cornwell AC, Maraszek KE, Paterson EJ, Kim M, Venkat S, et al. RNA. 2024 Feb 16; 30(3):281-297. Epub 2024 Feb 16.
Therapeutic targeting of CPSF3-dependent transcriptional termination in ovarian cancer. [Sci Adv. 2023]
Therapeutic targeting of CPSF3-dependent transcriptional termination in ovarian cancer.
Shen P, Ye K, Xiang H, Zhang Z, He Q, Zhang X, Cai MC, Chen J, Sun Y, Lin L, et al. Sci Adv. 2023 Nov 24; 9(47):eadj0123. Epub 2023 Nov 22.
A real-time fluorescence assay for CPSF73, the nuclease for pre-mRNA 3'-end processing. [RNA. 2021]
A real-time fluorescence assay for CPSF73, the nuclease for pre-mRNA 3'-end processing.
Gutierrez PA, Baughman K, Sun Y, Tong L. RNA. 2021 Oct; 27(10):1148-1154. Epub 2021 Jul 6.

RefSeq protein isoforms
See 7 reference sequence protein isoforms for the CPSF3 gene.

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Q9UKF6 [Domain Mapping of Disease Mut...]
Q9UKF6
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Cleavage and polyadenylation specificity factor subunit 3; AltName...
RecName: Full=Cleavage and polyadenylation specificity factor subunit 3; AltName: Full=Cleavage and polyadenylation specificity factor 73 kDa subunit; Short=CPSF 73 kDa subunit; AltName: Full=mRNA 3'-end-processing endonuclease CPSF-73
gi|18203503|sp|Q9UKF6.1|CPSF3_HUMAN

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