PMC Links for Protein (Select 125711) - PMC

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Select item 59035471.

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies

Ernest Turro, Daniel Greene, Anouck Wijgaerts, Chantal Thys, Claire Lentaigne, Tadbir K. Bariana, Sarah K. Westbury, Anne M. Kelly, Dominik Selleslag, Jonathan C. Stephens, Sofia Papadia, Ilenia Simeoni, Christopher J. Penkett, Sofie Ashford, Antony Attwood, Steve Austin, Tamam Bakchoul, Peter Collins, Sri V. V. Deevi, Rémi Favier, Myrto Kostadima, Michele P. Lambert, Mary Mathias, Carolyn M. Millar, Kathelijne Peerlinck, David J. Perry, Sol Schulman, Deborah Whitehorn, Christine Wittevrongel, BRIDGE-BPD Consortium, Marc De Maeyer, Augusto Rendon, Keith Gomez, Wendy N. Erber, Andrew D. Mumford, Paquita Nurden, Kathleen Stirrups, John R. Bradley, F. Lucy Raymond, Michael A. Laffan, Chris Van Geet, Sylvia Richardson, Kathleen Freson, Willem H. Ouwehand

Sci Transl Med. Author manuscript; available in PMC 2018 Apr 17.

Published in final edited form as: Sci Transl Med. 2016 Mar 2; 8(328): 328ra30. Published online 2016 Mar 2. doi: 10.1126/scitranslmed.aad7666

PMCID:: PMC5903547

Abstract Article PDF–1.9M

Select item 55896302.

Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK

Yilu Lu, Xulei Zheng, Wei Hu, Shasha Bian, Zhiwei Zhang, Dachang Tao, Yunqiang Liu, Yongxin Ma

Oncotarget. 2017 Aug 15; 8(33): 54913–54924. Published online 2017 Jul 4. doi: 10.18632/oncotarget.18973

PMCID:: PMC5589630

Abstract Article PDF–3.9M

Select item 36377903.

Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis

Soichiro Yoshida, Shinji Tsutsumi, Guillaume Muhlebach, Carole Sourbier, Min-Jung Lee, Sunmin Lee, Evangelia Vartholomaiou, Manabu Tatokoro, Kristin Beebe, Naoto Miyajima, Robert P. Mohney, Yang Chen, Hisashi Hasumi, Wanping Xu, Hiroshi Fukushima, Ken Nakamura, Fumitaka Koga, Kazunori Kihara, Jane Trepel, Didier Picard, Leonard Neckers

Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17): E1604–E1612. Published online 2013 Apr 5. doi: 10.1073/pnas.1220659110

PMCID:: PMC3637790

Abstract Article PDF–1.4M

Select item 36314344.

Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase non-receptor 14

Peng Zhang, Ailan Guo, Anthony Possemato, Chao Wang, Lydia Beard, Cathleen Carlin, Sanford D. Markowitz, Roberto D. Polakiewicz, Zhenghe Wang

Oncogene. Author manuscript; available in PMC 2013 Oct 18.

Published in final edited form as: Oncogene. 2013 Apr 18; 32(16): 2087–2095. Published online 2012 Jun 18. doi: 10.1038/onc.2012.220

PMCID:: PMC3631434

Abstract Article PDF–932K

Select item 31679405.

Cdk5 targets active Src for ubiquitin-dependent degradation by phosphorylating Src(S75)

Q. Pan, F. Qiao, C. Gao, B. Norman, L. Optican, Peggy S. Zelenka

Cell Mol Life Sci. 2011 Oct; 68(20): 3425–3436. Published online 2011 Mar 27. doi: 10.1007/s00018-011-0638-1

PMCID:: PMC3167940

Abstract Article PDF–2.0M

Select item 31033416.

PRR7 Is a Transmembrane Adaptor Protein Expressed in Activated T Cells Involved in Regulation of T Cell Receptor Signaling and Apoptosis

Matouš Hrdinka, Peter Dráber, Ondřej Štěpánek, Tereza Ormsby, Pavel Otáhal, Pavla Angelisová, Tomáš Brdička, Jan Pačes, Václav Hořejší, Karel Drbal

J Biol Chem. 2011 Jun 3; 286(22): 19617–19629. Published online 2011 Apr 1. doi: 10.1074/jbc.M110.175117

PMCID:: PMC3103341

Abstract Article PDF–4.5M

Select item 30846757.

A direct interaction between the large GTPase dynamin-2 and FAK regulates focal adhesion dynamics in response to active Src

Yu Wang, Hong Cao, Jing Chen, Mark A. McNiven

Mol Biol Cell. 2011 May 1; 22(9): 1529–1538. doi: 10.1091/mbc.E10-09-0785

PMCID:: PMC3084675

Abstract Article PDF–1.6M

Select item 30384098.

Heme Controls the Regulation of Protein Tyrosine Kinases Jak2 and Src

Xiao Yao, Parimaladevi Balamurugan, Aaron Arvey, Christina Leslie, Li Zhang

Biochem Biophys Res Commun. Author manuscript; available in PMC 2011 Dec 3.

Published in final edited form as: Biochem Biophys Res Commun. 2010 Dec 3; 403(1): 30–35. Published online 2010 Oct 29. doi: 10.1016/j.bbrc.2010.10.101

PMCID:: PMC3038409

Abstract Article PDF–732K

Select item 29112989.

The N Terminus of Cbl-c Regulates Ubiquitin Ligase Activity by Modulating Affinity for the Ubiquitin-conjugating Enzyme

Philip E. Ryan, Nina Sivadasan-Nair, Marion M. Nau, Sarah Nicholas, Stanley Lipkowitz

J Biol Chem. 2010 Jul 30; 285(31): 23687–23698. Published online 2010 Jun 4. doi: 10.1074/jbc.M109.091157

PMCID:: PMC2911298

Abstract Article PDF–1.7M

Select item 289510410.

Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2

Thomas Mund, Hugh R. B. Pelham

Proc Natl Acad Sci U S A. 2010 Jun 22; 107(25): 11429–11434. Published online 2010 Jun 7. doi: 10.1073/pnas.0911714107

PMCID:: PMC2895104

Abstract Article PDF–843K

Select item 284317411.

Src Kinase Phosphorylates RUNX3 at Tyrosine Residues and Localizes the Protein in the Cytoplasm

Yun-Mi Goh, Senthilkumar Cinghu, Eileen Tan Hwee Hong, You-Soub Lee, Jang-Hyun Kim, Ju-Won Jang, Ying-Hui Li, Xin-Zi Chi, Kyeong-Sook Lee, Heejun Wee, Yoshiaki Ito, Byung-Chul Oh, Suk-Chul Bae

J Biol Chem. 2010 Mar 26; 285(13): 10122–10129. Published online 2010 Jan 25. doi: 10.1074/jbc.M109.071381

PMCID:: PMC2843174

Abstract Article PDF–1.9M

Select item 271271912.

Patterns of somatic mutation in human cancer genomes

Christopher Greenman, Philip Stephens, Raffaella Smith, Gillian L. Dalgliesh, Christopher Hunter, Graham Bignell, Helen Davies, Jon Teague, Adam Butler, Claire Stevens, Sarah Edkins, Sarah O'Meara, Imre Vastrik, Esther E. Schmidt, Tim Avis, Syd Barthorpe, Gurpreet Bhamra, Gemma Buck, Bhudipa Choudhury, Jody Clements, Jennifer Cole, Ed Dicks, Simon Forbes, Kris Gray, Kelly Halliday, Rachel Harrison, Katy Hills, Jon Hinton, Andy Jenkinson, David Jones, Andy Menzies, Tatiana Mironenko, Janet Perry, Keiran Raine, Dave Richardson, Rebecca Shepherd, Alexandra Small, Calli Tofts, Jennifer Varian, Tony Webb, Sofie West, Sara Widaa, Andy Yates, Daniel P. Cahill, David N. Louis, Peter Goldstraw, Andrew G. Nicholson, Francis Brasseur, Leendert Looijenga, Barbara L. Weber, Yoke-Eng Chiew, Anna deFazio, Mel F. Greaves, Anthony R. Green, Peter Campbell, Ewan Birney, Douglas F. Easton, Georgia Chenevix-Trench, Min-Han Tan, Sok Kean Khoo, Bin Tean Teh, Siu Tsan Yuen, Suet Yi Leung, Richard Wooster, P. Andrew Futreal, Michael R. Stratton

Nature. Author manuscript; available in PMC 2009 Jul 20.

Published in final edited form as: Nature. 2007 Mar 8; 446(7132): 153–158. doi: 10.1038/nature05610

PMCID:: PMC2712719

Abstract Article PDF–867K

Select item 270919913.

Large-scale Proteomics Analysis of the Human Kinome

Felix S. Oppermann, Florian Gnad, Jesper V. Olsen, Renate Hornberger, Zoltán Greff, György Kéri, Matthias Mann, Henrik Daub

Mol Cell Proteomics. 2009 Jul; 8(7): 1751–1764. Published online 2009 Apr 15. doi: 10.1074/mcp.M800588-MCP200

PMCID:: PMC2709199

Abstract Article PDF–993K

Select item 270719314.

The Tyrosine Kinase c-Src Enhances RIG-I (Retinoic Acid-inducible Gene I)-elicited Antiviral Signaling

Ingvild B. Johnsen, Thuy Thanh Nguyen, Bjarte Bergstroem, Katherine A. Fitzgerald, Marit W. Anthonsen

J Biol Chem. 2009 Jul 10; 284(28): 19122–19131. Published online 2009 May 6. doi: 10.1074/jbc.M808233200

PMCID:: PMC2707193

Abstract Article PDF–1.8M

Select item 269914515.

Reversion-induced LIM interaction with Src reveals a novel Src inactivation cycle

Yongjun Zhang, Yizeng Tu, Jianping Zhao, Ka Chen, Chuanyue Wu

J Cell Biol. 2009 Mar 23; 184(6): 785–792. doi: 10.1083/jcb.200810155

PMCID:: PMC2699145

Abstract Article PDF–1.7M

Select item 261248716.

New Role for the Protein Tyrosine Phosphatase DEP-1 in Akt Activation and Endothelial Cell Survival

Catherine Chabot, Kathleen Spring, Jean-Philippe Gratton, Mounib Elchebly, Isabelle Royal

Mol Cell Biol. 2009 Jan; 29(1): 241–253. Published online 2008 Oct 20. doi: 10.1128/MCB.01374-08

PMCID:: PMC2612487

Abstract Article PDF–1.9M

Select item 217379717.

EphB1 recruits c-Src and p52^Shc to activate MAPK/ERK and promote chemotaxis

Cécile Vindis, Douglas Pat Cerretti, Thomas O. Daniel, Uyen Huynh-Do

J Cell Biol. 2003 Aug 18; 162(4): 661–671. doi: 10.1083/jcb.200302073

PMCID:: PMC2173797

Abstract Article PDF–496K

Select item 217336918.

Regulation of cytochrome c oxidase activity by c-Src in osteoclasts

Tsuyoshi Miyazaki, Lynn Neff, Sakae Tanaka, William C. Horne, Roland Baron

J Cell Biol. 2003 Mar 3; 160(5): 709–718. doi: 10.1083/jcb.200209098

PMCID:: PMC2173369

Abstract Article PDF–463K

Select item 189476519.

p140Cap protein suppresses tumour cell properties, regulating Csk and Src kinase activity

Paola Di Stefano, Laura Damiano, Sara Cabodi, Simona Aramu, Luca Tordella, Alice Praduroux, Roberto Piva, Federica Cavallo, Guido Forni, Lorenzo Silengo, Guido Tarone, Emilia Turco, Paola Defilippi

EMBO J. 2007 Jun 20; 26(12): 2843–2855. Published online 2007 May 24. doi: 10.1038/sj.emboj.7601724

PMCID:: PMC1894765

Abstract Article PDF–692K

Select item 143024120.

The Adaptor Protein Tom1L1 Is a Negative Regulator of Src Mitogenic Signaling Induced by Growth Factors

Mélanie Franco, Olivia Furstoss, Valérie Simon, Chrsitine Benistant, Wan Jing Hong, Serge Roche

Mol Cell Biol. 2006 Mar; 26(5): 1932–1947. doi: 10.1128/MCB.26.5.1932-1947.2006

PMCID:: PMC1430241

Abstract Article PDF–722K

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