PMC Links for Protein (Select 124486791) - PMC

Select item 68001161.

C9ORF72-ALS/FTD-associated poly(GR) binds Atp5a1 and compromises mitochondrial function in vivo

So Yoen Choi, Rodrigo Lopez-Gonzalez, Gopinath Krishnan, Hannah L. Phillips, Alissa Nana Li, William W. Seeley, Wei-Dong Yao, Sandra Almeida, Fen-Biao Gao

Nat Neurosci. Author manuscript; available in PMC 2019 Oct 18.

Published in final edited form as: Nat Neurosci. 2019 Jun; 22(6): 851–862. Published online 2019 May 13. doi: 10.1038/s41593-019-0397-0

PMCID:: PMC6800116

Article PDF–3.0M

Select item 62177312.

A C9orf72–CARM1 axis regulates lipid metabolism under glucose starvation-induced nutrient stress

Yang Liu, Tao Wang, Yon Ju Ji, Kenji Johnson, Honghe Liu, Kaitlin Johnson, Scott Bailey, Yongwon Suk, Yu-Ning Lu, Mingming Liu, Jiou Wang

Genes Dev. 2018 Nov 1; 32(21-22): 1380–1397. doi: 10.1101/gad.315564.118

PMCID:: PMC6217731

Article PDF–14M

Select item 61121563.

Haploinsufficiency Leads to Neurodegeneration in C9ORF72 ALS/FTD Human Induced Motor Neurons

Yingxiao Shi, Shaoyu Lin, Kim A. Staats, Yichen Li, Wen-Hsuan Chang, Shu-Ting Hung, Eric Hendricks, Gabriel R. Linares, Yaoming Wang, Esther Y. Son, Xinmei Wen, Kassandra Kisler, Brent Wilkinson, Louise Menendez, Tohru Sugawara, Phillip Woolwine, Mickey Huang, Michael J. Cowan, Brandon Ge, Nicole Koutsodendris, Kaitlin P. Sandor, Jacob Komberg, Vamshidhar R. Vangoor, Ketharini Senthilkumar, Valerie Hennes, Carina Seah, Amy R. Nelson, Tze-Yuan Cheng, Shih-Jong J. Lee, Paul R. August, Jason A. Chen, Nicholas Wisniewski, Hanson-Smith Victor, T. Grant Belgard, Alice Zhang, Marcelo Coba, Chris Grunseich, Michael E. Ward, Leonard H. van den Berg, R. Jeroen Pasterkamp, Davide Trotti, Berislav V. Zlokovic, Justin K. Ichida

Nat Med. Author manuscript; available in PMC 2018 Aug 28.

Published in final edited form as: Nat Med. 2018 Mar; 24(3): 313–325. Published online 2018 Feb 5. doi: 10.1038/nm.4490

PMCID:: PMC6112156

Article PDF–1.1M

Select item 60520264.

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy

Maneka Chitiprolu, Chantal Jagow, Veronique Tremblay, Emma Bondy-Chorney, Geneviève Paris, Alexandre Savard, Gareth Palidwor, Francesca A. Barry, Lorne Zinman, Julia Keith, Ekaterina Rogaeva, Janice Robertson, Mathieu Lavallée-Adam, John Woulfe, Jean-François Couture, Jocelyn Côté, Derrick Gibbings

Nat Commun. 2018; 9: 2794. Published online 2018 Jul 18. doi: 10.1038/s41467-018-05273-7

PMCID:: PMC6052026

Article PDF–5.8M

Select item 55158475.

Cell-type specific differences in promoter activity of the ALS-linked C9orf72 mouse ortholog

Abraham J. Langseth, Juhyun Kim, Janet E. Ugolino, Yajas Shah, Ho-Yon Hwang, Jiou Wang, Dwight E. Bergles, Solange P. Brown

Sci Rep. 2017; 7: 5685. Published online 2017 Jul 18. doi: 10.1038/s41598-017-05864-2

PMCID:: PMC5515847

Article PDF–5.5M

Select item 46923606.

C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits

Jeannie Chew, Tania F. Gendron, Mercedes Prudencio, Hiroki Sasaguri, Yong-Jie Zhang, Monica Castanedes-Casey, Chris W. Lee, Karen Jansen-West, Aishe Kurti, Melissa E. Murray, Kevin F. Bieniek, Peter O. Bauer, Ena C. Whitelaw, Linda Rousseau, Jeannette N. Stankowski, Caroline Stetler, Lillian M. Daughrity, Emilie A. Perkerson, Pamela Desaro, Amelia Johnston, Karen Overstreet, Dieter Edbauer, Rosa Rademakers, Kevin B. Boylan, Dennis W. Dickson, John D. Fryer, Leonard Petrucelli

Science. Author manuscript; available in PMC 2015 Dec 28.

Published in final edited form as: Science. 2015 Jun 5; 348(6239): 1151–1154. Published online 2015 May 14. doi: 10.1126/science.aaa9344

PMCID:: PMC4692360

Article PDF–1.8M

Select item 43979027.

The mouse C9ORF72 ortholog is enriched in neurons known to degenerate in ALS and FTD

Naoki Suzuki, Asif Maroof, Florian T Merkle, Kathryn Koszka, Atsushi Intoh, Ian Armstrong, Rob Moccia, Brandi N Davis-Dusenbery, Kevin Eggan

Nat Neurosci. Author manuscript; available in PMC 2015 Apr 15.

Published in final edited form as: Nat Neurosci. 2013 Dec; 16(12): 1725–1727. Published online 2013 Nov 3. doi: 10.1038/nn.3566

PMCID:: PMC4397902

Article PDF–1.7M

Select item 40493108.

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

Manal A. Farg, Vinod Sundaramoorthy, Jessica M. Sultana, Shu Yang, Rachel A.K. Atkinson, Vita Levina, Mark A. Halloran, Paul A. Gleeson, Ian P. Blair, Kai Y. Soo, Anna E. King, Julie D. Atkin

Hum Mol Genet. 2014 Jul 1; 23(13): 3579–3595. Published online 2014 Feb 18. doi: 10.1093/hmg/ddu068

Correction in:: Hum Mol Genet. 2017 Oct 15; 26(20): 4093–4094.

PMCID:: PMC4049310

Article PDF–1.8M

Select item 38397529.

Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration

Clotilde Lagier-Tourenne, Michael Baughn, Frank Rigo, Shuying Sun, Patrick Liu, Hai-Ri Li, Jie Jiang, Andrew T. Watt, Seung Chun, Melanie Katz, Jinsong Qiu, Ying Sun, Shuo-Chien Ling, Qiang Zhu, Magdalini Polymenidou, Kevin Drenner, Jonathan W. Artates, Melissa McAlonis-Downes, Sebastian Markmiller, Kasey R. Hutt, Donald P. Pizzo, Janet Cady, Matthew B. Harms, Robert H. Baloh, Scott R. Vandenberg, Gene W. Yeo, Xiang-Dong Fu, C. Frank Bennett, Don W. Cleveland, John Ravits

Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47): E4530–E4539. Published online 2013 Oct 29. doi: 10.1073/pnas.1318835110

PMCID:: PMC3839752

Article PDF–1.4M

Select item 381385810.

Highly Efficient Targeted Mutagenesis in Mice Using TALENs

Sudeepta Kumar Panda, Benedikt Wefers, Oskar Ortiz, Thomas Floss, Bettina Schmid, Christian Haass, Wolfgang Wurst, Ralf Kühn

Genetics. 2013 Nov; 195(3): 703–713. doi: 10.1534/genetics.113.156570

PMCID:: PMC3813858

Article PDF–2.8M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from Protein

Items: 10

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity