PMC Articles for PubChem Compound (Select 9868902) - PMC

Result Filters

Links from PubChem Compound

Items: 1 to 20 of 24

<< First< Prev

Page of 2

Select item 93613291.

Hypoxia-Induced Sarcoplasmic Reticulum Ca²⁺ Leak Is Reversed by Ryanodine Receptor Stabilizer JTV-519 in HL-1 Cardiomyocytes

Minh Duc Trinh, Ivana Fiserova, Lukas Vacek, Marek Heide, Jan Pala, Petr Tousek, Jan Polak

Anatol J Cardiol. 2022 Jun; 26(6): 476–484. Published online 2022 Jun 1. doi: 10.5152/AnatolJCardiol.2022.1223

PMCID:: PMC9361329

Abstract Article PDF–3.2M

Select item 66287872.

Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome

Sun-Ji Park, Yeawon Kim, Shyh-Ming Yang, Mark J. Henderson, Wei Yang, Maria Lindahl, Fumihiko Urano, Ying Maggie Chen

Proc Natl Acad Sci U S A. 2019 Jul 9; 116(28): 14154–14163. Published online 2019 Jun 24. doi: 10.1073/pnas.1813580116

PMCID:: PMC6628787

Abstract Article PDF–2.1M

Select item 59267663.

Reversal of Cisplatin Resistance by the 1,4‐Benzothiazepine Derivative, JTV‐519

Takashi Nakamura, Fumiaki Koizumi, Noboru Kaneko, Tomohide Tamura, Fumiko Chiwaki, Yasuhiro Koh, Shigeru Akutagawa, Nagahiro Saijo, Kazuto Nishio

Jpn J Cancer Res. 2001 Jun; 92(6): 597–602. doi: 10.1111/j.1349-7006.2001.tb01136.x

PMCID:: PMC5926766

Abstract Article PDF–98K

Select item 51648504.

Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs

Na Li, Qiongling Wang, Martha Sibrian-Vazquez, Robert C. Klipp, Julia O. Reynolds, Tarah A. Word, Larry Scott, Jr., Guy Salama, Robert M. Strongin, Jonathan J. Abramson, Xander H.T. Wehrens

Int J Cardiol. Author manuscript; available in PMC 2018 Jan 15.

Published in final edited form as: Int J Cardiol. 2017 Jan 15; 227: 668–673. Published online 2016 Oct 29. doi: 10.1016/j.ijcard.2016.10.078

PMCID:: PMC5164850

Abstract Article PDF–954K

Select item 44725655.

Synchronous Systolic Subcellular Ca²⁺-Elevations Underlie Ventricular Arrhythmia in Drug-Induced Long QT Type 2

Jong J. Kim, Jan Němec, Qiao Li, Guy Salama

Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2016 Jun 1.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2015 Jun; 8(3): 703–712. Published online 2015 Feb 26. doi: 10.1161/CIRCEP.114.002214

PMCID:: PMC4472565

Abstract Article PDF–1.0M

Select item 42891366.

2APB- and JTV519(K201)-sensitive micro Ca²⁺ waves in arrhythmogenic Purkinje cells that survive in infarcted canine heart

Penelope A. Boyden, Wen Dun, Chirag Barbhaiya, Henk E.D.J. ter Keurs

Heart Rhythm. Author manuscript; available in PMC 2015 Jan 10.

Published in final edited form as: Heart Rhythm. 2004 Jul; 1(2): 218–226. doi: 10.1016/j.hrthm.2004.03.068

PMCID:: PMC4289136

Abstract Article PDF–480K

Select item 38411417.

Effect of Calstabin1 Depletion on Calcium Transients and Energy Utilization in Muscle Fibers and Treatment Opportunities with RyR1 Stabilizers

Anke Breckner, Magdalena Ganz, David Marcellin, Jens Richter, Nicole Gerwin, Martin Rausch

PLoS One. 2013; 8(11): e81277. Published online 2013 Nov 26. doi: 10.1371/journal.pone.0081277

PMCID:: PMC3841141

Abstract Article PDF–667K

Select item 36027728.

Bradycardia alters Ca²⁺ dynamics enhancing dispersion of repolarization and arrhythmia risk

Jong J. Kim, Jan Němec, Rita Papp, Robert Strongin, Jonathan J. Abramson, Guy Salama

Am J Physiol Heart Circ Physiol. 2013 Mar 15; 304(6): H848–H860. Published online 2013 Jan 11. doi: 10.1152/ajpheart.00787.2012

PMCID:: PMC3602772

Abstract Article

Select item 34492559.

JTV519 (K201) reduces sarcoplasmic reticulum Ca²⁺ leak and improves diastolic function in vitro in murine and human non-failing myocardium

M Sacherer, S Sedej, P Wakuła, M Wallner, MA Vos, J Kockskämper, P Stiegler, M Sereinigg, D von Lewinski, G Antoons, BM Pieske, FR Heinzel, on behalf of CONTICA investigators

Br J Pharmacol. 2012 Oct; 167(3): 493–504. doi: 10.1111/j.1476-5381.2012.01995.x

PMCID:: PMC3449255

Abstract Article PDF–2.2M

Select item 334624310.

The effect of K201 on isolated working rabbit heart mechanical function during pharmacologically induced Ca²⁺ overload

A Kelly, EB Elliott, R Matsuda, N Kaneko, GL Smith, CM Loughrey

Br J Pharmacol. 2012 Feb; 165(4b): 1068–1083. doi: 10.1111/j.1476-5381.2011.01531.x

PMCID:: PMC3346243

Abstract Article PDF–2.4M

Select item 325011111.

Designing Calcium Release Channel Inhibitors with Enhanced Electron Donor Properties: Stabilizing the Closed State of Ryanodine Receptor Type 1

Yanping Ye, Daniel Yaeger, Laura J. Owen, Jorge O. Escobedo, Jialu Wang, Jeffrey D. Singer, Robert M. Strongin, Jonathan J. Abramson

Mol Pharmacol. 2012 Jan; 81(1): 53–62. doi: 10.1124/mol.111.074740

PMCID:: PMC3250111

Abstract Article PDF–1.8M

Select item 322895612.

K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca²⁺ release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes

E. B. Elliott, H. Hasumi, N. Otani, T. Matsuda, R. Matsuda, N. Kaneko, G. L. Smith, Christopher M. Loughrey

Basic Res Cardiol. 2011; 106(6): 1009–1022. Published online 2011 Sep 8. doi: 10.1007/s00395-011-0218-4

PMCID:: PMC3228956

Abstract Article PDF–806K

Select item 288390113.

Calcium polymorphic ventricular tachycardia: a new name for CPVT?

Fabien Brette

Cardiovasc Res. 2010 Jul 1; 87(1): 10–11. Published online 2010 May 13. doi: 10.1093/cvr/cvq128

PMCID:: PMC2883901

Article PDF–72K

Select item 284142714.

Pharmacological Characteristics and Clinical Applications of K201

Noboru Kaneko, Ryuko Matsuda, Yoshihito Hata, Ken Shimamoto

Curr Clin Pharmacol. 2009 May; 4(2): 126–131. doi: 10.2174/157488409788184972

PMCID:: PMC2841427

Abstract Article PDF–351K

Select item 280796715.

K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca²⁺ leak from the sarcoplasmic reticulum

Karl Toischer, Stephan E. Lehnart, Gero Tenderich, Hendrik Milting, Reiner Körfer, Jan D. Schmitto, Friedrich A. Schöndube, Noboru Kaneko, Christopher M. Loughrey, Godfrey L. Smith, Gerd Hasenfuss, Tim Seidler

Basic Res Cardiol. 2010; 105(2): 279–287. Published online 2009 Aug 30. doi: 10.1007/s00395-009-0057-8