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Select item 68773321.

Slowing ribosome velocity restores folding and function of mutant CFTR

Kathryn E. Oliver, Robert Rauscher, Marjolein Mijnders, Wei Wang, Matthew J. Wolpert, Jessica Maya, Carleen M. Sabusap, Robert A. Kesterson, Kevin L. Kirk, Andras Rab, Ineke Braakman, Jeong S. Hong, John L. Hartman, IV, Zoya Ignatova, Eric J. Sorscher

J Clin Invest. 2019 Dec 2; 129(12): 5236–5253. Published online 2019 Oct 28. doi: 10.1172/JCI124282

PMCID:: PMC6877332

Article PDF–5.3M

Select item 67203792.

Reduced expression of the Ion channel CFTR contributes to airspace enlargement as a consequence of aging and in response to cigarette smoke in mice

Jack H. Wellmerling, Sheng-Wei Chang, Eunsoo Kim, Wissam H. Osman, Prosper N. Boyaka, Michael T. Borchers, Estelle Cormet-Boyaka

Respir Res. 2019; 20: 200. Published online 2019 Sep 2. doi: 10.1186/s12931-019-1170-3

PMCID:: PMC6720379

Article PDF–971K

Select item 66941373.

A BAC Transgene Expressing Human CFTR under Control of Its Regulatory Elements Rescues Cftr Knockout Mice

Lara R. Gawenis, Craig A. Hodges, Daniel R. McHugh, Dana M. Valerio, Alexander Miron, Calvin U. Cotton, Jinghua Liu, Nancy M. Walker, Ashlee M. Strubberg, Austin E. Gillen, Michael J. Mutolo, George Kotzamanis, Jürgen Bosch, Ann Harris, Mitchell L. Drumm, Lane L. Clarke

Sci Rep. 2019; 9: 11828. Published online 2019 Aug 14. doi: 10.1038/s41598-019-48105-4

PMCID:: PMC6694137

Article PDF–2.7M

Select item 66144494.

Targeting DNAJB9, a novel ER luminal co-chaperone, to rescue ΔF508-CFTR

Yunjie Huang, Kavisha Arora, Kyu Shik Mun, Fanmuyi Yang, ChangSuk Moon, Sunitha Yarlagadda, Anil Jegga, Timothy Weaver, Anjaparavanda P. Naren

Sci Rep. 2019; 9: 9808. Published online 2019 Jul 8. doi: 10.1038/s41598-019-46161-4

PMCID:: PMC6614449

Article PDF–2.9M

Select item 65991195.

Evaluation of eluforsen, a novel RNA oligonucleotide for restoration of CFTR function in in vitro and murine models of p.Phe508del cystic fibrosis

Wouter Beumer, Jim Swildens, Teresinha Leal, Sabrina Noel, Herma Anthonijsz, Geert van der Horst, Hester Kuiperij-Boersma, Marko Potman, Charlotte van Putten, Patricia Biasutto, Gerard Platenburg, Hugo de Jonge, Noreen Henig, Tita Ritsema

PLoS One. 2019; 14(6): e0219182. Published online 2019 Jun 28. doi: 10.1371/journal.pone.0219182

PMCID:: PMC6599119

Article PDF–2.6M

Select item 69087396.

Slc4a11 disruption causes duct cell loss and impairs NaCl reabsorption in female mouse submandibular glands

Ning‐Yan Yang, Taro Mukaibo, Xin Gao, Ira Kurtz, James E. Melvin

Physiol Rep. 2019 Dec; 7(23): e14232. Published online 2019 Dec 12. doi: 10.14814/phy2.14232

PMCID:: PMC6908739

Article PDF–2.8M

Select item 67978587.

Control of Ion Transport by Tmem16a Expressed in Murine Intestine

Karl Kunzelmann, Raquel Centeio, Podchanart Wanitchakool, Inês Cabrita, Roberta Benedetto, Tultul Saha, Kazi Mirajul Hoque, Rainer Schreiber

Front Physiol. 2019; 10: 1262. Published online 2019 Oct 4. doi: 10.3389/fphys.2019.01262

PMCID:: PMC6797858

Article PDF–5.1M

Select item 65858648.

Normal Calcium-Activated Anion Secretion in a Mouse Selectively Lacking TMEM16A in Intestinal Epithelium

Génesis Vega, Anita Guequén, Malin E. V. Johansson, Liisa Arike, Beatriz Martínez-Abad, Elisabeth E. L. Nyström, Paolo Scudieri, Nicoletta Pedemonte, Pamela Millar-Büchner, Amber R. Philp, Luis J. Galietta, Gunnar C. Hansson, Carlos A. Flores

Front Physiol. 2019; 10: 694. Published online 2019 Jun 13. doi: 10.3389/fphys.2019.00694

Correction in:: Front Physiol. 2019; 10: 1040.

PMCID:: PMC6585864

Article PDF–1020K

Select item 60877289.

Dextran sulfate sodium-induced chronic colitis attenuates Ca²⁺-activated Cl⁻ secretion in murine colon by downregulating TMEM16A

Trey S. Rottgen, Andrew J. Nickerson, Emily A. Minor, Amanda B. Stewart, Abby D. Harold, Vazhaikkurichi M. Rajendran

Am J Physiol Cell Physiol. 2018 Jul 1; 315(1): C10–C20. Published online 2018 Mar 21. doi: 10.1152/ajpcell.00328.2017

PMCID:: PMC6087728

Article

Select item 547237510.

Androgen receptor-deficient islet β-cells exhibit alteration in genetic markers of insulin secretion and inflammation. A transcriptome analysis in the male mouse

Weiwei Xu, Tianhua Niu, Beibei Xu, Guadalupe Navarro, Matthew J. Schipma, Franck Mauvais-Jarvis

J Diabetes Complications. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: J Diabetes Complications. 2017 May; 31(5): 787–795. Published online 2017 Mar 9. doi: 10.1016/j.jdiacomp.2017.03.002

PMCID:: PMC5472375

Article PDF–1.0M

Select item 543264811.

Deletion of Slc26a1 and Slc26a7 Delays Enamel Mineralization in Mice

Kaifeng Yin, Jing Guo, Wenting Lin, Sarah Y. T. Robertson, Manoocher Soleimani, Michael L. Paine

Front Physiol. 2017; 8: 307. Published online 2017 May 16. doi: 10.3389/fphys.2017.00307

PMCID:: PMC5432648

Article PDF–3.1M

Select item 497619012.

The Potential Role of 8-Oxoguanine DNA Glycosylase-Driven DNA Base Excision Repair in Exercise-Induced Asthma

KarryAnne K. Belanger, Bill T. Ameredes, Istvan Boldogh, Leopoldo Aguilera-Aguirre

Mediators Inflamm. 2016; 2016: 3762561. Published online 2016 Jul 25. doi: 10.1155/2016/3762561

PMCID:: PMC4976190

Article PDF–8.8M

Select item 371100913.

Putative interaction of brush cells with bicarbonate secreting cells in the proximal corpus mucosa

Julia Anna-Maria Eberle, Kai L. Müller-Roth, Patricia Widmayer, Vladimir Chubanov, Thomas Gudermann, Heinz Breer

Front Physiol. 2013; 4: 182. Published online 2013 Jul 15. doi: 10.3389/fphys.2013.00182

PMCID:: PMC3711009

Article PDF–1.8M

Select item 356641214.

Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes

Anastasia Renzi, Sharon DeMorrow, Paolo Onori, Guido Carpino, Romina Mancinelli, Fanyin Meng, Julie Venter, Mellanie White, Antonio Franchitto, Heather Francis, Yuyan Han, Yoshiyuki Ueno, Giuseppina Dusio, Kendal J Jensen, John J Greene, Jr., Shannon Glaser, Eugenio Gaudio, Gianfranco Alpini

Hepatology. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Hepatology. 2013 Mar; 57(3): 1130–1141. Published online 2013 Feb 7. doi: 10.1002/hep.26105

PMCID:: PMC3566412

Article PDF–3.2M

Select item 341370315.

Relating the Disease Mutation Spectrum to the Evolution of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

Lavanya Rishishwar, Neha Varghese, Eishita Tyagi, Stephen C. Harvey, I. King Jordan, Nael A. McCarty

PLoS One. 2012; 7(8): e42336. Published online 2012 Aug 7. doi: 10.1371/journal.pone.0042336

PMCID:: PMC3413703

Article PDF–1.6M

Select item 300877016.

Altered Ion-responsive Gene Expression in Mmp20 Null Mice

C.E. Tye, R. Sharma, C.E. Smith, J.D. Bartlett

J Dent Res. 2010 Dec; 89(12): 1421–1426. doi: 10.1177/0022034510384625

PMCID:: PMC3008770

Article PDF–293K

Select item 286739617.

The switch of intestinal Slc26 exchangers from anion absorptive to HCO₃⁻ secretory mode is dependent on CFTR anion channel function

Anurag Kumar Singh, Brigitte Riederer, Mingmin Chen, Fang Xiao, Anja Krabbenhöft, Regina Engelhardt, Olof Nylander, Manoocher Soleimani, Ursula Seidler

Am J Physiol Cell Physiol. 2010 May; 298(5): C1057–C1065. Published online 2010 Feb 17. doi: 10.1152/ajpcell.00454.2009

PMCID:: PMC2867396

Article

Select item 284245218.

THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR) IS EXPRESSED IN MATURATION STAGE AMELOBLASTS, ODONTOBLASTS AND BONE CELLS

Antonius Bronckers, Lida Kalogeraki, Huub J.N. Jorna, Martina Wilke, Theodore J. Bervoets, Donacian M. Lyaruu, Behrouz Zandieh-Doulabi, Pamela DenBesten, Hugo de Jonge

Bone. Author manuscript; available in PMC 2011 Apr 1.

Published in final edited form as: Bone. 2010 Apr; 46(4): 1188–1196. Published online 2009 Dec 30. doi: 10.1016/j.bone.2009.12.002

PMCID:: PMC2842452

Article PDF–3.3M

Select item 281100519.

Functional properties and evolutionary splicing constraints on a composite exonic regulatory element of splicing in CFTR exon 12

Ariful Haque, Emanuele Buratti, Francisco E. Baralle

Nucleic Acids Res. 2010 Jan; 38(2): 647–659. Published online 2009 Nov 12. doi: 10.1093/nar/gkp1040

PMCID:: PMC2811005

Article PDF–682K

Select item 270784420.

Transcriptional Dysregulation in a Transgenic Model of Parkinson’s Disease

Talene A. Yacoubian, Ippolita Cantuti-Castelvetri, Bérengère Bouzou, Georgios Asteris, Pamela J. McLean, Bradley T. Hyman, David G. Standaert

Neurobiol Dis. Author manuscript; available in PMC 2009 Jul 9.

Published in final edited form as: Neurobiol Dis. 2008 Mar; 29(3): 515–528. Published online 2007 Nov 28. doi: 10.1016/j.nbd.2007.11.008

PMCID:: PMC2707844

Article PDF–1.2M

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